To save researchers time and resources, The Michael J. Fox Foundation has made a number of tools available to the scientific community at low cost, with rapid delivery.
Helpful Resources
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Sponsored Tools Program
Learn more about how MJFF can help share your tools.
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Tools Consortium
MJFF is working with industry to develop priority tools.
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Preclinical Models
Learn more about the various in vivo models used in Parkinson's disease research.
Find a Research Tool
Filter by Tool Type or Gene/Protein Type to Organize Results
* = MJFF does not control pricing or terms of availability for this tool.
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Mouse/Human Total Alpha-Synuclein Assay
Assay
AlphaLISA® SureFire® Ultra™ immunoassay kit for detection of Human and Mouse total alpha-synuclein.
NOD2 Edited iPSC Lines
Human iPS Cell
KOLF2.1J human iPSC line with CRISPR-engineered mutations in NOD2, including heterozygous and homozygous knockout, heterozygous, and homozygous knockout mutations. These lines were generated within the iPSC Neurodegeneration Initiative for Parkinson’s Disease (iNDI-PD) which is supported by Aligning Science Across Parkinson's (ASAP). Estimated Availability: Q1 2026.
Oligomeric Alpha-Synuclein Protein*
Protein
Stable oligomeric aggregates of alpha-synuclein protein. Intended for use in biochemical assays (not intended for use in the pre-formed fibril model).
OMP25 Antibody
Antibody
Rabbit monoclonal antibody directed against human/mouse OMP25 for immunoprecipitation of endogenous mitochondria.
Estimated Availability: Late 2025
Oxidized-DJ-1-Specific Antibody
Antibody
Rabbit monoclonal phosphospecific antibody directed against oxidized DJ-1 protein.
p62 pT138 Phosphospecific Antibody
Antibody
Rabbit monoclonal phosphospecific antibody directed against Threonine 138 of the p62 protein. Suitable for immunoblotting applications.
Parkin K161N KI Mouse*
Mouse Model
Mice with the K161N mutation in Parkin. Model was generated and deposited by Dr David Komander at Walter and Eliza Hall Institute of Medical Research through the MJFF Sponsored Tools Program.
Estimated Availability: Late 2024
Parkin Knockout Mouse*
Mouse Model
Homozygous knockout mice with exon 3 mutation resulting in a frame shift and a premature stop codon in exon 5. Model was generated and deposited by Jie Shen at Harvard Medical School Brigham and Women’s Hospital through the MJFF Sponsored Tools Program. RRID:IMSR_JAX:006582
Parkin KO Rat
Rat Model
CRISPR/Cas9 genome targeting strategy to knockout Parkin on a Sprague Dawley rat background.
Estimated Availability: Late 2025
Parkin KO Rat*
Rat Model
Homozygous rat knockout of Parkin in the Long Evans Hooded rat strain. RRID:RGD_7241052
Have questions or need additional information?
Email tools@michaeljfox.org with questions and to suggest new tools for us to develop. Or visit our FAQ page.
"We have shown, thanks in part to MJFF, that researchers now have in their pantry the right ‘ingredients’, to... help to drive forward PD drug development.”
Heather Melrose, PhD
Mayo Clinic