To save researchers time and resources, The Michael J. Fox Foundation has made a number of tools available to the scientific community at low cost, with rapid delivery.
Helpful Resources
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Sponsored Tools Program
Learn more about how MJFF can help share your tools.
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Tools Consortium
MJFF is working with industry to develop priority tools.
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Preclinical Models
Learn more about the various in vivo models used in Parkinson's disease research.
Find a Research Tool
Filter by Tool Type or Gene/Protein Type to Organize Results
* = MJFF does not control pricing or terms of availability for this tool.
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PINK1 KO Rat
Rat Model
CRISPR/Cas9 genome targeting strategy to knockout PINK1 on a Sprague Dawley rat background.
Estimated Availability: Late 2025
PINK1 KO Rat*
Rat Model
Homozygous rat knockout of Pink1 (PTEN-induced putative kinase 1) in the Long Evans Hooded rat strain. RRID:RGD_7241054
PINK1 Plasmids
DNA Plasmids
DNA Plasmids encoding various PINK1 cDNA inserts
PINK1 pS228 Phosphospecific Antibody
Antibody
Rabbit monoclonal phosphospecific antibody directed against Serine 228 of PINK1.
Expected Availability: Early 2025
PINK1 pT257 Phosphospecific Antibody
Antibody
Rabbit monoclonal phosphospecific antibody directed against Threonine 257 of human PINK1. Suitable for immunoblot applications.
PPMI iPSCs
Human iPS Cell
Induced pluripotent stem cell (iPSC) lines are available through the PPMI repository. The repository includes lines from control, idiopathic PD, genetic PD (LRRK2, GBA, SNCA), genetic unaffected carriers (LRRK2, LRRK2/GBA, GBA, SNCA), and prodromal patients. Gene-revertant controls are available for select lines. An inventory of available lines can be found here: https://zenodo.org/records/10783308
PRKN Edited iPSC Lines
Human iPS Cell
KOLF2.1J human iPSC line with CRISPR-engineered mutations in PRKN, including heterozygous and homozygous R275W, T240M, R42P, and P437L mutations. These lines were generated within the iPSC Neurodegeneration Initiative for Parkinson’s Disease (iNDI-PD) which is supported by Aligning Science Across Parkinson's (ASAP).
pS65 Parkin Antibody (WB/ICC)
Antibody
Rabbit monoclonal phosphospecific antibody directed against Serine65 of Parkin. Compatible with immunoblotting and immunocytochemistry applications.
pS65 Ubiquitin Immunoassay*
Assay
SMCxPRO® immunoassay for measurement of phospho-serine 65 Ubiquitin. Assay was developed and kindly shared by Mitokinin through the MJFF Sponsored Tools Program.
To access, complete the request form on the Millipore CADI services page.
PSMF1 Edited iPSC Lines
Human iPS Cell
KOLF2.1J human iPSC line with CRISPR-engineered mutations in PSMF1, including heterozygous and homozygous R242C and R231*, and homozygous knockout mutations. These lines were generated within the iPSC Neurodegeneration Initiative for Parkinson’s Disease (iNDI-PD) which is supported by Aligning Science Across Parkinson's (ASAP). Estimated Availability: Q1 2026.
Have questions or need additional information?
Email tools@michaeljfox.org with questions and to suggest new tools for us to develop. Or visit our FAQ page.
"We have shown, thanks in part to MJFF, that researchers now have in their pantry the right ‘ingredients’, to... help to drive forward PD drug development.”
Heather Melrose, PhD
Mayo Clinic