To save researchers time and resources, The Michael J. Fox Foundation has made a number of tools available to the scientific community at low cost, with rapid delivery.
Helpful Resources
-
Sponsored Tools Program
Learn more about how MJFF can help share your tools.
-
Tools Consortium
MJFF is working with industry to develop priority tools.
-
Preclinical Models
Learn more about the various in vivo models used in Parkinson's disease research.
Find a Research Tool
Filter by Tool Type or Gene/Protein Type to Organize Results
* = MJFF does not control pricing or terms of availability for this tool.
Filters
GBA IVS2+1 Human ES Cell Line
Immortalized Cell
Modified WIBR3 Human ES cell line with GBA IVS2+1 mutation. This line was generated as part of the iSCORE-PD (Isogenic Stem Cell Collection to Research Parkinson’s Disease) collection created through a collaboration between the Soldner Lab, Albert Einstein College of Medicine, Hockemeyer Lab, University of California, Berkeley, Bateup Lab, University of California, Berkeley, and Rio Lab, University of California, Berkeley, and developed under the Aligning Science Across Parkinson’s (ASAP) initiative.
Parkin Exon 3 Deletion Human ES Cell Line
Immortalized Cell
Modified WIBR3 Human ES cell line with PRKN Exon 3 deletion. This line was generated as part of the iSCORE-PD (Isogenic Stem Cell Collection to Research Parkinson’s Disease) collection created through a collaboration between the Soldner Lab, Albert Einstein College of Medicine, Hockemeyer Lab, University of California, Berkeley, Bateup Lab, University of California, Berkeley, and Rio Lab, University of California, Berkeley, and developed under the Aligning Science Across Parkinson’s (ASAP) initiative.
PINK1 Q129X Human ES Cell Line
Immortalized Cell
Modified WIBR3 Human ES cell line with PINK1 Q129X mutation. This line was generated as part of the iSCORE-PD (Isogenic Stem Cell Collection to Research Parkinson’s Disease) collection created through a collaboration between the Soldner Lab, Albert Einstein College of Medicine, Hockemeyer Lab, University of California, Berkeley, Bateup Lab, University of California, Berkeley, and Rio Lab, University of California, Berkeley, and developed under the Aligning Science Across Parkinson’s (ASAP) initiative.
FBXO7 Frameshift Human ES Cell Line
Immortalized Cell
Modified WIBR3 Human ES cell line with FBXO7 Frameshift mutation. This line was generated as part of the iSCORE-PD (Isogenic Stem Cell Collection to Research Parkinson’s Disease) collection created through a collaboration between the Soldner Lab, Albert Einstein College of Medicine, Hockemeyer Lab, University of California, Berkeley, Bateup Lab, University of California, Berkeley, and Rio Lab, University of California, Berkeley, and developed under the Aligning Science Across Parkinson’s (ASAP) initiative. Estimated Availability: Q3 2026
FBXO7 R498X Human ES Cell Line
Immortalized Cell
Modified WIBR3 Human ES cell line with FBXO7 R498X mutation. This line was generated as part of the iSCORE-PD (Isogenic Stem Cell Collection to Research Parkinson’s Disease) collection created through a collaboration between the Soldner Lab, Albert Einstein College of Medicine, Hockemeyer Lab, University of California, Berkeley, Bateup Lab, University of California, Berkeley, and Rio Lab, University of California, Berkeley, and developed under the Aligning Science Across Parkinson’s (ASAP) initiative. Estimated Availability: Q3 2026
DNAJC6 Frameshift Human ES Cell Line
Immortalized Cell
Modified WIBR3 Human ES cell line with DNAJC6 Frameshift mutation. This line was generated as part of the iSCORE-PD (Isogenic Stem Cell Collection to Research Parkinson’s Disease) collection created through a collaboration between the Soldner Lab, Albert Einstein College of Medicine, Hockemeyer Lab, University of California, Berkeley, Bateup Lab, University of California, Berkeley, and Rio Lab, University of California, Berkeley, and developed under the Aligning Science Across Parkinson’s (ASAP) initiative. Estimated Availability: Q3 2026
DNAJC6 Splice Variant Human ES Cell Line
Immortalized Cell
Modified WIBR3 Human ES cell line with DNAJC6 Splice Variant mutation. This line was generated as part of the iSCORE-PD (Isogenic Stem Cell Collection to Research Parkinson’s Disease) collection created through a collaboration between the Soldner Lab, Albert Einstein College of Medicine, Hockemeyer Lab, University of California, Berkeley, Bateup Lab, University of California, Berkeley, and Rio Lab, University of California, Berkeley, and developed under the Aligning Science Across Parkinson’s (ASAP) initiative. Estimated Availability: Q3 2026
CLN3 Edited iPSC Lines
Human iPS Cell
KOLF2.1J human iPSC line with CRISPR-engineered mutations in CLN3, including -Knockout (homozygous)-R334H (heterozygous and homozygous) - in development, est Q3 2026-V330I (heterozygous and homozygous) - in development, est Q3 2026These lines were generated within the iPSC Neurodegeneration Initiative for Parkinson’s Disease (iNDI-PD) which is supported by the Aligning Science Across Parkinson’s (ASAP) Initiative.
PSMF1 Edited iPSC Lines
Human iPS Cell
KOLF2.1J human iPSC line with CRISPR-engineered mutations in PSMF1, including - -R231* (heterozygous and homozygous) - in development, est Q3 2026
- -R242C (heterozygous and homozygous) - in development, est Q3 2026
- -Knockout (homozygous)
SMPD1 Edited iPSC Lines
Human iPS Cell
KOLF2.1J human iPSC line with CRISPR-engineered mutations in SMPD1, including - -Q294K (heterozygous and homozygous) - in development, est Q3 2026
- -L262Rfs*s (heterozygous and homozygous) - in development, est Q3 2026
- -Knockout (homozygous)
Have questions or need additional information?
Email tools@michaeljfox.org with questions and to suggest new tools for us to develop. Or visit our FAQ page.
"We have shown, thanks in part to MJFF, that researchers now have in their pantry the right ‘ingredients’, to... help to drive forward PD drug development.”
Heather Melrose, PhD
Mayo Clinic