Dr. Cagla Eroglu investigates the roles of astrocytes in the development, remodeling, function and dysfunction of synaptic circuits. Her research elucidated important molecular mechanisms that underlie astrocytic control of synapse formation in health and disease. She has a deep molecular and cellular understanding of neuronal and glial cell biology, synapse formation and receptor-ligand interactions. She is an expert in the methodologies needed to assess glial and neural anatomy and synaptic connectivity in vitro and in vivo. Through the use of cutting-edge imaging and image analyses techniques, her lab identifies and characterizes novel glia-neuron signaling pathways that control synaptic circuit assembly with the aim to translate their basic science findings into strategies to reestablish proper brain function after injury or disease. In particular, they are investigating how manipulation of astrocyte-neuron signaling can be an effective therapeutic target to cure synaptic pathologies seen in neurological disorders, including Parkinson’s disease.