… of Parkinson’s disease (PD) is growing but remains far from complete. Unfortunately, most of this research has not … about Parkinson’s in populations that have been excluded from or underrepresented in the research. These groups …

… follows the work of the Parkinson’s Action Network (PAN). From 1991 to 2016, PAN served as the unified voice of the … and loved ones on Capitol Hill and worked, with input from other Parkinson’s organizations, to positively impact …

… to toxic chemicals during service. The committee heard from activists and advocates, including The Michael J. Fox … on this topic. Service members are exposed to toxins from garbage burn pits, as well as warfare chemicals, …

… explore the published literature and collect information from focus group sessions with people with PD and their care … improve identification of people with PD who might benefit from early treatment and facilitate the evaluation of …

… and the processing of alpha-synuclein in neurons derived from people with GBA-associated PD. Now, we seek to further … Hypothesis:  Based on prior work in neurons derived from people with PD, we predict that activation of TRPML1 …

… of alpha-synuclein and tau converts these proteins from a biologically functional state into toxic, fibrous … by either alpha-synuclein fibrils or tau fibrils derived from a post mortem AD brain. We will conduct these studies …