The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Understanding LRRK2 Biology, 2009Functional Analysis of LRRK2
Objective/Rationale:
LRRK2 is a gene that, when not working properly, causes Parkinson’s disease. However, the function of this large gene and its involvement in the disease process is virtually... -
Understanding LRRK2 Biology, 2009Development of Biochemical Assays for LRRK1
Objective/Rationale:
Studies over the last several years have identified the protein kinase LRRK2 as a potential target for Parkinson’s disease therapeutics. While targeting kinases has been a... -
Biomarkers, 2009T-Cell Receptors Changes as a Biomarker of Parkinson's Disease
Objective/Rationale:
The diagnosis of PD is based on clinical characteristics because there are no reliable blood tests for early diagnosis or to follow the progressive course of the disease. Along... -
Target Validation, 2009Testing PDE-1 Inhibitor in MPTP-treated Macaques
Promising Outcomes of Original Grant:
Our goal is to develop novel therapeutic molecules that promote normal dopamine neurotransmission in the brain affected by PD. We hypothesize that these molecules... -
Critical Challenges in PD: Alpha-synuclein Neuroimaging, 2009Development and Screening of Contrast Agents for In Vivo Imaging of PD
Objective/Rationale:
This project aims to develop reagents to image alpha-synuclein pathology in the brains of living patients as a PD specific biomarker.
Project Description:
Using a library of small... -
Critical Challenges in PD: Alpha-synuclein Neuroimaging, 2009Utility of the Amyloid Ligand [18F]FDDNP in Human PET Imaging in Parkinson Disease
Objective/Rationale:
Biomarkers of Parkinson disease are sorely needed for the assessment of disease status so that they may be used to design more efficient and informative clinical trials of disease...
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Our funding programs support basic, translational and clinical research from academia and industry.