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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Diversity, Equity and Inclusivity in Parkinson's research, 2022
    Studying Parkinson’s Disease Clinical Features, Progression and Quality of Care in Latino Patients from a Population-based Epidemiological Study in the United States

    Study Rationale: Social and medical factors can affect the rates of Parkinson’s disease (PD) and how the disorder manifests in different individuals. These factors may carry different weight in...

  • [RFA] Use of PD Biosamples - Spring 2020, 2022
    Studying DNA Methylation in Parkinson’s Disease Using the Systemic Synuclein Sampling Study

    Study Rationale: Developing accurate and reliable biomarkers for Parkinson’s disease (PD) is critical for detecting early changes with the hope of better understanding the mechanisms of disease and...

  • Research Grant, 2022
    Developing a Method for Detecting Alpha-synuclein in the Acidic Cell Compartments in Which It Accumulates

    Study Rationale: The protein alpha-synuclein forms harmful clusters or aggregates that can kill neurons in the brains of people with Parkinson’s disease (PD). Neurons attempt to eliminate these clumps...

  • Research Grant, 2022
    Pharmacokinetics, Food Effects, Safety and Tolerability of Aggregation Inhibitor Anle138b in Parkinson´s Disease

    Study Rationale:
    Pathological alpha-synuclein aggregates, called Lewy bodies, are a hallmark of Parkinson’s disease (PD) and a promising target for therapeutics. Anle138b is a compound that inhibits...

  • Fall 2021 RFP: Expanding Biological Understanding of PD, 2022
    Exploring How Mutations in Genes Associated with Parkinson’s Disease Alter the Activity of Other Genes

    Study Rationale: Population studies have identified genetic changes that raise an individual’s risk of developing Parkinson’s disease (PD). However, this information doesn't help people if we don’t...

  • Diversity, Equity and Inclusivity in Parkinson's research, 2022
    Multiculturalism, Reported Cognitive Complaints and Predictors of Cognitive Decline Following Deep Brain Stimulation

    Study Rationale: Cognitive decline is common in people with Parkinson’s disease (PD), and changes in thinking and performance on objective cognitive tests reported by individuals and their family are...

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