The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Non-pharmacological Interventions for Gait and Balance, 2019Vibrating Socks: A Novel Cueing Intervention to Reduce Freezing of Gait in Parkinson's Disease
Study Rationale:
Freezing of gait is a common and disabling symptom in Parkinson's disease. With freezing of gait, patients have the feeling that their feet are suddenly glued to the floor when they... -
Biomarkers of Protein Handling/Autophagy, Exosomes and Lipid, 2019Studying Blood Proteins to Improve Diagnosis and Tracking of Parkinson's Disease
Study Rationale:
Mutations (changes) in protein LRRK2 is the main genetic cause of Parkinson's disease (PD). In the past, we found that LRRK2 interacts with ribosomes, cellular protein factories. We... -
Alpha-synculein Biology and Therapies, 2018Ordering the Earliest Neuronal Response Events to Native Alpha-synuclein Exposure
Study Rationale:
The protein alpha-synuclein forms aggregates in the brains of people with Parkinson’s. Here, we will not look at the end stage of protein aggregation and cell death, which has been... -
Alpha-synculein Biology and Therapies, 2018Structure and Function of Alpha-synuclein at the Pre-synapse
Study Rationale:
Current therapeutic strategies against synucleinopathies aim to either stabilize a native form of alpha-synuclein or to reduce its levels in patients. However, the normal... -
GBA Biology and Therapies, 2018Sphingolipid and Alpha-synuclein Interactions
Study Rationale:
In Parkinson’s, a normal cellular protein called alpha-synuclein begins to fold incorrectly (misfold), and this has a central role in the development of the disease. Our research... -
Alpha-synculein Biology and Therapies, 2018Effects of Post-translational Modifications on Alpha-synuclein Aggregation
Study Rationale:
Evidence suggests that the protein alpha-synuclein can cause the death of neurons in the brains of people with Parkinson’s disease (PD) by forming clusters (or aggregates) on the...
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Our funding programs support basic, translational and clinical research from academia and industry.