The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Rapid Response Innovation Awards, 2010Identification and Validation of the Modifiers of LRRK2-induced Toxicity
Objective/Rationale:
Mutations in LRRK2 gene have been identified as an unambiguous cause of rare autosomal dominant forms of PD. A number of useful models have been developed to study the... -
Rapid Response Innovation Awards, 2010Protecting Innervation: Nmnat1 Gene Therapy for Parkinson's Disease
Objective/Rationale:
Axonal degeneration is a major pathological hallmark of Parkinson’s disease (PD). Evidence gathered in PD patients indicates that pathology in axons occurs prior to and... -
Rapid Response Innovation Awards, 2010CSF Lysosomal Hydrolases' Activity as Possible Marker of Parkinson's Disease
Objective/Rationale:
Recent studies have linked lysosomal dysfunction to the accumulation of alpha-synuclein oligomers and alpha-synuclein-mediated cell death. Clinical, neuropathological and genetic... -
Rapid Response Innovation Awards, 2010Genetic-epidemiological Confirmation of Top Hits of GWAS of Parkinson Disease: A Large Multi-center Collaborative Study
Objective/Rationale:
A critical question which is still unresolved in the post GWAS (genome-wide association study) era focuses on the role of non genetic factors conferring either a risk or... -
Rapid Response Innovation Awards, 2010Development of a Progressive Familial Pre-clinical Model of Parkinson's Disease
Objective/Rationale:
Although a number of genes have been identified that lead to Parkinson’s disease in humans, the scientific community has yet to be able to recapitulate this in pre-clinical... -
Clinical Intervention Awards, 2010Gastric-Retentive, Extended-Release Levodopa/Carbidopa Tablets Versus a Reference, Extended-Release Tablet in Parkinson's Disease
Objective/Rationale:
The objective of this project is to develop a gastric-retentive, extended-release tablet of levodopa/carbidopa (DM-1992) that will result in constant blood levels of levodopa...
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Our funding programs support basic, translational and clinical research from academia and industry.