The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Research Grant, 2013Cutaneous Alpha-Synuclein Deposition — A Biomarker in Parkinson’s Disease
Objective/Rationale:
There is an unmet need for a biomarker in Parkinson’s disease (PD). Accumulating evidence suggests that deposition of alpha-synuclein, the pathological hallmark of PD... -
Rapid Response Innovation Awards, 2013Creation of the “BiSyn” Model: a Novel Tool to Monitor Alpha-synuclein Aggregation
Objective/Rationale:
The cause of Parkinson’s disease (PD) is unknown. However, it has become clear that the abnormal aggregation of a neuronal protein called alpha-synuclein has an... -
Biosample and Tissue Resource, 2013Alpha-synuclein Three Prime Untranslated Region (3’UTR) Modulation in Parkinson's Disease
Objective/Rationale:
New technology shows that many genes are transcribed (the first step in genetic expression) as multiple, different forms of RNA (molecules that play a role in genetic... -
Rapid Response Innovation Awards, 2013Control of the Nigrostriatal Pathway by the Tail of the Ventral Tegmental Area
Objective/Rationale:
Neuroanatomical inputs to the substantia nigra pars compacta (SNc) modulate the activity of dopamine neurons and could influence the symptoms of Parkinson’s disease. A new brain... -
Biosample and Tissue Resource, 2013Assessing Glucocerebrosidase in Sporadic Parkinson’s Disease
Objective/Rationale:
Mutations in the glucocerebrosidase (GBA) gene are the most common genetic risk factor for Parkinson’s disease (PD). These mutations are present in approximately seven... -
Research Grant, 2013Exosome/Microvesicle Release from LRRK2 Mutant iPSC-derived Neural Cells
Objective/Rationale:
Exosomes/microvesicles are small vesicles that are shed from the cell membrane and are known to play a role in communication between cells. Exosomes/microvesicles...
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Our funding programs support basic, translational and clinical research from academia and industry.