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The Parkinson's Progression Markers Initiative is our landmark study launched in 2010 to deepen knowledge of Parkinson's and to better understand its onset and progression to speed the development of new treatments. Learn the latest news from the study here.


  • Man and woman smiling at camera.

    My Research Journey: I Don’t Have Parkinson’s, But I Could Help Stop It

    Brian Duggan shares what it’s like to live with REM sleep behavior disorder and to participate in research as part of the larger “at-risk” Parkinson’s community.

  • Woman sitting in wheelchair at doctor's office

    My Research Journey: A Practical Way of Managing Parkinson’s

    Jen Gaudio, one of the first ever PPMI participants, shares why she participates in research as a practical and constructive way to manage Parkinson’s.

  • Scientist in lab holding up blood sample

    PPMI Dispatch: Meeting of the Study Minds and Clues on Cognitive Change

    More than 300 study partners met virtually for the annual PPMI meeting to discuss challenges, opportunities and future plans while scientists continue to report out from study analysis.

  • Brian Duggan

    PPMI: Our Study to Predict and Prevent Parkinson’s Needs You

    For more than 10 years, thousands of patients, scientists and volunteers have contributed to The Michael J. Fox Foundation’s (MJFF) landmark study, the Parkinson’s Progression Markers Initiative …

  • Researcher-computer

    PPMI Dispatch: More Sites Recruiting While Scientists Uncover New Ways to Predict Parkinson’s

    While the Parkinson’s Progression Markers Initiative (PPMI) starts recruiting volunteers at 26 sites, research into existing data and biosamples continues.

  • Ask the MD: How to Get the Most out of Your Doctor's Appointment

    PPMI Needs People At Risk for Parkinson’s — Even if Not Diagnosed with PD

    PPMI is entering its next phase: an ambitious expansion of its study population to include individuals without a Parkinson’s diagnosis, but living with certain factors now known to be linked to…

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