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6181 - 6190 of 8620 Results
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  • Astrocytic α2-Na + /K + ATPase inhibition suppresses astrocyte reactivity and reduces neurodegeneration in a tauopathy mouse model
    2022
    Summary Details
    OPEN
    Title: Astrocytic α2-Na + /K + ATPase inhibition suppresses astrocyte reactivity and reduces neurodegeneration in a tauopathy mouse model
    Author(s): Carolyn N. Mann, Shamulailatpam Shreedarshanee Devi, Corey T. Kersting, Amber V. Bleem, Celeste M. Karch, David M. Holtzman, Gilbert Gallardo
    Journal Name: Science Translational Medicine
    Publisher: American Association for the Advancement of Science (AAAS)
    Vol: 14
    Issue #: 632
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1126/scitranslmed.abm4107
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/9161722
    Citation Count: 64
  • Monitoring gait at home with radio waves in Parkinson’s disease: A marker of severity, progression, and medication response
    2022
    Summary Details
    RESTRICTED
    Title: Monitoring gait at home with radio waves in Parkinson’s disease: A marker of severity, progression, and medication response
    Author(s): Yingcheng Liu, Guo Zhang, Christopher G. Tarolli, Rumen Hristov, Stella Jensen-Roberts, Emma Waddell, Taylor Myers, Meghan Pawlik, Julia Soto, Renée Wilson, Yuzhe Yang, Timothy Nordahl, Karlo J. Lizárraga, Jamie Adams, Ruth B. Schneider, Karl Kieburtz, Terry D. Ellis, E. Ray Dorsey, Dina Katabi
    Journal Name: Science Translational Medicine
    Publisher: American Association for the Advancement of Science (AAAS)
    Vol: 14
    Issue #: 663
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1126/scitranslmed.adc9669
    Best OA location URL:
    Citation Count: 66
  • Preclinical and clinical evaluation of the LRRK2 inhibitor DNL201 for Parkinson’s disease
    2022
    Summary Details
    RESTRICTED
    Title: Preclinical and clinical evaluation of the LRRK2 inhibitor DNL201 for Parkinson’s disease
    Author(s): Danna Jennings, Sarah Huntwork‐Rodriguez, Anastasia G. Henry, Jennifer C. Sasaki, René Meisner, Dolores Diaz, Hilda Solanoy, Xiang Wang, Elvira Negrou, Vitaliy V. Bondar, Rajarshi Ghosh, Michael T. Maloney, Nicholas E. Propson, Yuda Zhu, Romeo Maciuca, Laura Harris, Angela Kay, Peter A. LeWitt, T. Alex King, Drew S. Kern, Aaron Ellenbogen, Ira Goodman, Andrew Siderowf, Jason Aldred, Omid Omidvar, Shababa T. Masoud, Sonnet S. Davis, Annie Arguello, Anthony A. Estrada, Javier de Vicente, Zachary K. Sweeney, Giuseppe Astarita, Marie T. Borin, Bradley K. Wong, Harvey Wong, Hoang N. Nguyen, Kimberly Scearce‐Levie, Carole Ho, Matthew D. Troyer
    Journal Name: Science Translational Medicine
    Publisher: American Association for the Advancement of Science (AAAS)
    Vol: 14
    Issue #: 648
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1126/scitranslmed.abj2658
    Best OA location URL:
    Citation Count: 163
  • Library-Derived Peptide Aggregation Modulators of Parkinson’s Disease Early-Onset α-Synuclein Variants
    2022
    Summary Details
    OPEN
    Title: Library-Derived Peptide Aggregation Modulators of Parkinson’s Disease Early-Onset α-Synuclein Variants
    Author(s): Kathryn J.C. Watt, Richard M. Meade, Robert J. Williams, Jody M. Mason
    Journal Name: ACS Chemical Neuroscience
    Publisher: American Chemical Society (ACS)
    Vol: 13
    Issue #: 12
    Start Page: 1790
    End Page: 1804
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1021/acschemneuro.2c00190
    Best OA location URL: https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.2c00190
    Citation Count: 4
  • Untwisted α-Synuclein Filaments Formed in the Presence of Lipid Vesicles
    2022
    Summary Details
    OPEN
    Title: Untwisted α-Synuclein Filaments Formed in the Presence of Lipid Vesicles
    Author(s): Anvesh K. R. Dasari, Lucas Dillard, Sujung Yi, Elizabeth Viverette, Alimohammad Hojjatian, Urmi Sengupta, Rakez Kayed, Kenneth A. Taylor, Mario J. Borgnia, Kwang Hun Lim
    Journal Name: Biochemistry
    Publisher: American Chemical Society (ACS)
    Vol: 61
    Issue #: 17
    Start Page: 1766
    End Page: 1773
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1021/acs.biochem.2c00283
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/10289115
    Citation Count: 9
  • Discovery and Optimization of Potent, Selective, and Brain-Penetrant 1-Heteroaryl-1H-Indazole LRRK2 Kinase Inhibitors for the Treatment of Parkinson’s Disease
    2022
    Summary Details
    RESTRICTED
    Title: Discovery and Optimization of Potent, Selective, and Brain-Penetrant 1-Heteroaryl-1H-Indazole LRRK2 Kinase Inhibitors for the Treatment of Parkinson’s Disease
    Author(s): David A. Candito, Vladimir Simov, Anmol Gulati, Solomon D. Kattar, Ryan Chau, Blair T. Lapointe, Joey L. Methot, Duane E. DeMong, Thomas H. Graham, Ravi Kurukulasuriya, Mitchell H. Keylor, Ling Tong, Gregori J. Morriello, John J. Acton, Barbara Pio, Weiguo Liu, Jack D. Scott, Michael J. Ardolino, Theodore A. Martinot, Matthew L. Maddess, Xin Yan, Hakan Günaydin, Rachel L. Palte, Spencer E. McMinn, Lisa Nogle, Hongshi Yu, Ellen C. Minnihan, Charles A. Lesburg, Ping Liu, Jing Su, Laxminarayan G. Hegde, Lily Y. Moy, Janice D. Woodhouse, Robert Faltus, Tina Xiong, Paul J. Ciaccio, Jennifer Piesvaux, Karin M. Otte, Matthew Kennedy, David Jonathan Bennett, Erin F. DiMauro, Matthew Fell, Santhosh Neelamkavil, Harold B. Wood, Peter H. Fuller, J. Michael Ellis
    Journal Name: Journal of Medicinal Chemistry
    Publisher: American Chemical Society (ACS)
    Vol: 65
    Issue #: 24
    Start Page: 16801
    End Page: 16817
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1021/acs.jmedchem.2c01605
    Best OA location URL:
    Citation Count: 16
  • How Prolonged Isolation Affects People With Parkinson Disease During the COVID-19 Pandemic
    2022
    Summary Details
    OPEN
    Title: How Prolonged Isolation Affects People With Parkinson Disease During the COVID-19 Pandemic
    Author(s): Melissa Suran
    Journal Name: JAMA
    Publisher: American Medical Association (AMA)
    Vol: 327
    Issue #: 9
    Start Page: 801
    End Page: 801
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1001/jama.2022.1510
    Best OA location URL: https://jamanetwork.com/journals/jama/articlepdf/2789055/jama_suran_2022_mn_220006_1645750114.50702.pdf
    Citation Count: 6
  • Frequency of and factors associated with antiseizure medication discontinuation discussions and decisions in patients with epilepsy: A multicenter retrospective chart review
    2023
    Summary Details
    OPEN
    Title: Frequency of and factors associated with antiseizure medication discontinuation discussions and decisions in patients with epilepsy: A multicenter retrospective chart review
    Author(s): Samuel W. Terman, Geertruida Slinger, Adriana Koek, Jeremy Skvarce, Mellanie V. Springer, Julie Ziobro, James Burke, Willem M. Otte, Roland D. Thijs, Kees P. J. Braun
    Journal Name: Epilepsia Open
    Publisher: Wiley
    Vol: 8
    Issue #: 2
    Start Page: 371
    End Page: 385
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1002/epi4.12695
    Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/epi4.12695
    Citation Count: 7
  • The Impact of the COVID‐19 Pandemic on Care Partners of People with Parkinson's Disease
    2023
    Summary Details
    OPEN
    Title: The Impact of the COVID‐19 Pandemic on Care Partners of People with Parkinson's Disease
    Author(s): Henricus Berend Speelberg, Max J. Hulshoff, Elaine Book, Nabila Dahodwala, Monica Korell, Caroline M. Tanner, Connie Marras
    Journal Name: Movement Disorders Clinical Practice
    Publisher: Wiley
    Vol: 10
    Issue #: 4
    Start Page: 596
    End Page: 605
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1002/mdc3.13678
    Best OA location URL: https://escholarship.org/content/qt2wb861nd/qt2wb861nd.pdf
    Citation Count: 1
  • Quantified Striatal Dopaminergic Denervation as Predictor for Motor Outcomes in Parkinson's Disease
    2023
    Summary Details
    OPEN
    Title: Quantified Striatal Dopaminergic Denervation as Predictor for Motor Outcomes in Parkinson's Disease
    Author(s): Ilene Trinh, Angeni Muralidhar, Justin Yang, Nicolás Phielipp
    Journal Name: Movement Disorders Clinical Practice
    Publisher: Wiley
    Vol: 10
    Issue #: 6
    Start Page: 896
    End Page: 902
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1002/mdc3.13726
    Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mdc3.13726
    Citation Count: 1
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