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Year
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  • Interferon gamma stimulates coordinated changes in LRRK2, GCase, and cathepsin activities in idiopathic and genetic Parkinson’s disease monocytes
    2025
    Summary Details
    OPEN
    Title: Interferon gamma stimulates coordinated changes in LRRK2, GCase, and cathepsin activities in idiopathic and genetic Parkinson’s disease monocytes
    Author(s): Laura P. Hughes, Rebecca L. Wallings, Julian Agin‐Liebes, Roy N. Alcalay, Alicia Garrido, Malú Gámez Tansey, Nicolas Dzamko
    Journal Name: npj Parkinson's Disease
    Publisher: Springer Science and Business Media LLC
    Vol: 11
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s41531-025-01185-8
    Best OA location URL: https://www.nature.com/articles/s41531-025-01185-8.pdf
    Citation Count: 0
  • Adenosine in the Brain: Recent Progress on Detection, Function, and Translation
    2025
    Summary Details
    RESTRICTED
    Title: Adenosine in the Brain: Recent Progress on Detection, Function, and Translation
    Author(s): Takaki Yahiro, Philip Hwang, Francesca Logiacco, Kathryn L. Todd, Stephanie J. Cragg, Luísa V. Lopes, Anne Shaefer, Zhaofa Wu, Jiang-Fan Chen, Haining Zhong
    Journal Name: The Journal of Neuroscience
    Publisher: Society for Neuroscience
    Vol: 45
    Issue #: 46
    Start Page: e1377252025
    End Page: e1377252025
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1523/jneurosci.1377-25.2025
    Citation Count: 0
  • High‐molecular‐weight oligomer tau ( HMWoTau ) species are dramatically increased in Braak‐stage dependent manner in the frontal lobe of human brains, demonstrated by a novel oligomer Tau ELISA with a mouse monoclonal antibody ( APNmAb005 )
    2024
    Summary Details
    OPEN
    Title: High‐molecular‐weight oligomer tau ( HMWoTau ) species are dramatically increased in Braak‐stage dependent manner in the frontal lobe of human brains, demonstrated by a novel oligomer Tau ELISA with a mouse monoclonal antibody ( APNmAb005 )
    Author(s): Hiroaki Fukumoto, Tzu‐Huei Kao, Chin‐Yin Tai, Ming‐Kuei Jang, Masaomi Miyamoto
    Journal Name: The FASEB Journal
    Publisher: Wiley
    Vol: 38
    Issue #: 22
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1096/fj.202401704r
    Best OA location URL: https://doi.org/10.1096/fj.202401704r
    Citation Count: 3
  • LRRK2 inhibitors induce reversible changes in nonhuman primate lungs without measurable pulmonary deficits
    2020
    Summary Details
    OPEN
    Title: LRRK2 inhibitors induce reversible changes in nonhuman primate lungs without measurable pulmonary deficits
    Author(s): Marco A. S. Baptista, Kalpana Merchant, Ted Barrett, Sakshi Bhargava, Dianne K. Bryce, J. Michael Ellis, Anthony A. Estrada, Matthew Fell, Brian Fiske, Reina N. Fuji, Paul Galatsis, Anastasia G. Henry, Sue Hill, Warren D. Hirst, Christopher Houle, Matthew Kennedy, Xingrong Liu, Matthew L. Maddess, Carrie G. Markgraf, Hong Mei, William A. Meier, Elie Needle, Stephen Ploch, Christopher M. Royer, Karin Rudolph, Alok Sharma, Antonia F. Stepan, Stefanus J. Steyn, Craig Trost, Zhizhang Yin, Hongshi Yu, Xiang Wang, Todd Sherer
    Journal Name: Science Translational Medicine
    Publisher: American Association for the Advancement of Science (AAAS)
    Vol: 12
    Issue #: 540
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1126/scitranslmed.aav0820
    Citation Count: 114
  • No Association Between Rare TWNK Variants and Parkinson's Disease in European Cohorts
    2022
    Summary Details
    RESTRICTED
    Title: No Association Between Rare TWNK Variants and Parkinson's Disease in European Cohorts
    Author(s): Konstantin Senkevich, Ziv Gan‐Or
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 37
    Issue #: 11
    Start Page: 2318
    End Page: 2319
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1002/mds.29216
    Citation Count: 4
  • Conversion of Quinazoline Modulators from Inhibitors to Activators of β-Glucocerebrosidase
    2019
    Summary Details
    OPEN
    Title: Conversion of Quinazoline Modulators from Inhibitors to Activators of β-Glucocerebrosidase
    Author(s): Jianbin Zheng, Sohee Jeon, Weilan Jiang, Lena F. Burbulla, Daniel Ysselstein, Kristine Oevel, Dimitri Krainc, Richard B. Silverman
    Journal Name: Journal of Medicinal Chemistry
    Publisher: American Chemical Society (ACS)
    Vol: 62
    Issue #: 3
    Start Page: 1218
    End Page: 1230
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1021/acs.jmedchem.8b01294
    Best OA location URL: https://doi.org/10.7270/q280562c
    Citation Count: 23
  • Selective metabotropic glutamate receptor 2 positive allosteric modulation alleviates L-DOPA-induced psychosis-like behaviours and dyskinesia in the MPTP-lesioned marmoset
    2020
    Summary Details
    RESTRICTED
    Title: Selective metabotropic glutamate receptor 2 positive allosteric modulation alleviates L-DOPA-induced psychosis-like behaviours and dyskinesia in the MPTP-lesioned marmoset
    Author(s): Lamia Sid‐Otmane, Adjia Hamadjida, Stephen G. Nuara, Dominique Bédard, Fleur Gaudette, Jim C. Gourdon, Véronique Michaud, Francis Beaudry, Michel Panisset, Philippe Huot
    Journal Name: European Journal of Pharmacology
    Publisher: Elsevier BV
    Vol: 873
    Issue #:
    Start Page: 172957
    End Page: 172957
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.ejphar.2020.172957
    Citation Count: 29
  • Altered reward-related neural responses in non-manifesting carriers of the Parkinson disease related LRRK2 mutation
    2018
    Summary Details
    RESTRICTED
    Title: Altered reward-related neural responses in non-manifesting carriers of the Parkinson disease related LRRK2 mutation
    Author(s): Avner Thaler, Tal Gonen, Anat Mirelman, Rick C. Helmich, Tanya Gurevich, Avi Orr‐Urtreger, Bastiaan R. Bloem, Nir Giladi, Talma Hendler
    Journal Name: Brain Imaging and Behavior
    Publisher: Springer Science and Business Media LLC
    Vol: 13
    Issue #: 4
    Start Page: 1009
    End Page: 1020
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1007/s11682-018-9920-2
    Citation Count: 16
  • Binding of the Human 14-3-3 Isoforms to Distinct Sites in the Leucine-Rich Repeat Kinase 2
    2020
    Summary Details
    OPEN
    Title: Binding of the Human 14-3-3 Isoforms to Distinct Sites in the Leucine-Rich Repeat Kinase 2
    Author(s): Jascha T. Manschwetus, Maximilian Wallbott, Alexandra Fachinger, Claudia Obergruber, Sabine Pautz, Daniela Bertinetti, Sven H. Schmidt, Friedrich W. Herberg
    Journal Name: Frontiers in Neuroscience
    Publisher: Frontiers Media SA
    Vol: 14
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.3389/fnins.2020.00302
    Best OA location URL: https://www.frontiersin.org/articles/10.3389/fnins.2020.00302/pdf
    Citation Count: 56
  • Objective characterization of daily living transitions in patients with Parkinson’s disease using a single body-fixed sensor
    2016
    Summary Details
    RESTRICTED
    Title: Objective characterization of daily living transitions in patients with Parkinson’s disease using a single body-fixed sensor
    Author(s): Hagar Bernad‐Elazari, Talia Herman, Anat Mirelman, Eran Gazit, Nir Giladi, Jeffrey M. Hausdorff
    Journal Name: Journal of Neurology
    Publisher: Springer Science and Business Media LLC
    Vol: 263
    Issue #: 8
    Start Page: 1544
    End Page: 1551
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1007/s00415-016-8164-6
    Citation Count: 46
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