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7101 - 7110 of 8587 Results
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Year
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  • Unveiling the B cell receptor structure
    2022
    Summary Details
    OPEN
    Title: Unveiling the B cell receptor structure
    Author(s): Pavel Tolar, Susan K. Pierce
    Journal Name: Science
    Publisher: American Association for the Advancement of Science (AAAS)
    Vol: 377
    Issue #: 6608
    Start Page: 819
    End Page: 820
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1126/science.add8065
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/11044948
    Citation Count: 10
  • Toward preventing Parkinson’s disease
    2022
    Summary Details
    RESTRICTED
    Title: Toward preventing Parkinson’s disease
    Author(s): Brit Mollenhauer, Christine A. F. Von Arnim
    Journal Name: Science
    Publisher: American Association for the Advancement of Science (AAAS)
    Vol: 377
    Issue #: 6608
    Start Page: 818
    End Page: 819
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1126/science.add7162
    Best OA location URL: https://resolver.sub.uni-goettingen.de/purl?gro-2/113804
    Citation Count: 15
  • A NAC domain mutation (E83Q) unlocks the pathogenicity of human alpha-synuclein and recapitulates its pathological diversity
    2022
    Summary Details
    OPEN
    Title: A NAC domain mutation (E83Q) unlocks the pathogenicity of human alpha-synuclein and recapitulates its pathological diversity
    Author(s): Senthil T. Kumar, Anne‐Laure Mahul‐Mellier, Ramanath Narayana Hegde, Gwladys Rivière, Rani Moons, Alain Ibáñez de Opakua, Pedro Magalhães, Iman Rostami, Sonia Donzelli, Frank Sobott, Markus Zweckstetter, Hilal A. Lashuel
    Journal Name: Science Advances
    Publisher: American Association for the Advancement of Science (AAAS)
    Vol: 8
    Issue #: 17
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1126/sciadv.abn0044
    Best OA location URL: https://www.science.org/doi/pdf/10.1126/sciadv.abn0044?download=true
    Citation Count: 30
  • GPNMB confers risk for Parkinson’s disease through interaction with α-synuclein
    2022
    Summary Details
    OPEN
    Title: GPNMB confers risk for Parkinson’s disease through interaction with α-synuclein
    Author(s): Maria E. Diaz‐Ortiz, Yunji Seo, Marijan Posavi, Marc Carceles Cordon, Elisia Clark, Nimansha Jain, Rakshita A. Charan, Michael D. Gallagher, Travis L. Unger, Noor Amari, R. Tyler Skrinak, Roseanne Davila‐Rivera, Eliza M. Brody, Noah Han, Rebecca Zack, Vivianna M. Van Deerlin, Thomas F. Tropea, Kelvin C. Luk, Edward B. Lee, Daniel Weintraub, Alice Chen‐Plotkin
    Journal Name: Science
    Publisher: American Association for the Advancement of Science (AAAS)
    Vol: 377
    Issue #: 6608
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1126/science.abk0637
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/9870036
    Citation Count: 103
  • Membrane curvature sensing and stabilization by the autophagic LC3 lipidation machinery
    2022
    Summary Details
    OPEN
    Title: Membrane curvature sensing and stabilization by the autophagic LC3 lipidation machinery
    Author(s): Liv Jensen, Shanlin Rao, Martina Schuschnig, A. King Cada, Sascha Martens, Gerhard Hummer, James H. Hurley
    Journal Name: Science Advances
    Publisher: American Association for the Advancement of Science (AAAS)
    Vol: 8
    Issue #: 50
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc, cc-by
    DOI - Digital Object Identifier: 10.1126/sciadv.add1436
    Best OA location URL: https://escholarship.org/uc/item/39r5f1mn
    Citation Count: 36
  • Comprehensive genetic diagnosis of tandem repeat expansion disorders with programmable targeted nanopore sequencing
    2022
    Summary Details
    OPEN
    Title: Comprehensive genetic diagnosis of tandem repeat expansion disorders with programmable targeted nanopore sequencing
    Author(s): Igor Stevanovski, Sanjog R. Chintalaphani, Hasindu Gamaarachchi, James M. Ferguson, Sandy S. Pineda, Carolin K. Scriba, Michel Tchan, Victor S.C. Fung, Karl Ng, Andrea Cortese, Henry Houlden, Carol Dobson‐Stone, Lauren Fitzpatrick, Glenda M. Halliday, Gianina Ravenscroft, Mark R. Davis, Nigel G. Laing, Avi Fellner, Marina Kennerson, Kishore R. Kumar, Ira W. Deveson
    Journal Name: Science Advances
    Publisher: American Association for the Advancement of Science (AAAS)
    Vol: 8
    Issue #: 9
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1126/sciadv.abm5386
    Best OA location URL: https://www.science.org/doi/pdf/10.1126/sciadv.abm5386
    Citation Count: 131
  • Astrocytic α2-Na + /K + ATPase inhibition suppresses astrocyte reactivity and reduces neurodegeneration in a tauopathy mouse model
    2022
    Summary Details
    OPEN
    Title: Astrocytic α2-Na + /K + ATPase inhibition suppresses astrocyte reactivity and reduces neurodegeneration in a tauopathy mouse model
    Author(s): Carolyn N. Mann, Shamulailatpam Shreedarshanee Devi, Corey T. Kersting, Amber V. Bleem, Celeste M. Karch, David M. Holtzman, Gilbert Gallardo
    Journal Name: Science Translational Medicine
    Publisher: American Association for the Advancement of Science (AAAS)
    Vol: 14
    Issue #: 632
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1126/scitranslmed.abm4107
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/9161722
    Citation Count: 64
  • Library-Derived Peptide Aggregation Modulators of Parkinson’s Disease Early-Onset α-Synuclein Variants
    2022
    Summary Details
    OPEN
    Title: Library-Derived Peptide Aggregation Modulators of Parkinson’s Disease Early-Onset α-Synuclein Variants
    Author(s): Kathryn J.C. Watt, Richard M. Meade, Robert J. Williams, Jody M. Mason
    Journal Name: ACS Chemical Neuroscience
    Publisher: American Chemical Society (ACS)
    Vol: 13
    Issue #: 12
    Start Page: 1790
    End Page: 1804
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1021/acschemneuro.2c00190
    Best OA location URL: https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.2c00190
    Citation Count: 4
  • Untwisted α-Synuclein Filaments Formed in the Presence of Lipid Vesicles
    2022
    Summary Details
    OPEN
    Title: Untwisted α-Synuclein Filaments Formed in the Presence of Lipid Vesicles
    Author(s): Anvesh K. R. Dasari, Lucas Dillard, Sujung Yi, Elizabeth Viverette, Alimohammad Hojjatian, Urmi Sengupta, Rakez Kayed, Kenneth A. Taylor, Mario J. Borgnia, Kwang Hun Lim
    Journal Name: Biochemistry
    Publisher: American Chemical Society (ACS)
    Vol: 61
    Issue #: 17
    Start Page: 1766
    End Page: 1773
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1021/acs.biochem.2c00283
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/10289115
    Citation Count: 9
  • Discovery and Optimization of Potent, Selective, and Brain-Penetrant 1-Heteroaryl-1H-Indazole LRRK2 Kinase Inhibitors for the Treatment of Parkinson’s Disease
    2022
    Summary Details
    RESTRICTED
    Title: Discovery and Optimization of Potent, Selective, and Brain-Penetrant 1-Heteroaryl-1H-Indazole LRRK2 Kinase Inhibitors for the Treatment of Parkinson’s Disease
    Author(s): David A. Candito, Vladimir Simov, Anmol Gulati, Solomon D. Kattar, Ryan Chau, Blair T. Lapointe, Joey L. Methot, Duane E. DeMong, Thomas H. Graham, Ravi Kurukulasuriya, Mitchell H. Keylor, Ling Tong, Gregori J. Morriello, John J. Acton, Barbara Pio, Weiguo Liu, Jack D. Scott, Michael J. Ardolino, Theodore A. Martinot, Matthew L. Maddess, Xin Yan, Hakan Günaydin, Rachel L. Palte, Spencer E. McMinn, Lisa Nogle, Hongshi Yu, Ellen C. Minnihan, Charles A. Lesburg, Ping Liu, Jing Su, Laxminarayan G. Hegde, Lily Y. Moy, Janice D. Woodhouse, Robert Faltus, Tina Xiong, Paul J. Ciaccio, Jennifer Piesvaux, Karin M. Otte, Matthew Kennedy, David Jonathan Bennett, Erin F. DiMauro, Matthew Fell, Santhosh Neelamkavil, Harold B. Wood, Peter H. Fuller, J. Michael Ellis
    Journal Name: Journal of Medicinal Chemistry
    Publisher: American Chemical Society (ACS)
    Vol: 65
    Issue #: 24
    Start Page: 16801
    End Page: 16817
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1021/acs.jmedchem.2c01605
    Best OA location URL:
    Citation Count: 16
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