-
Another Leap Forward for LRRK2 Development
August 25, 2016
… today announced it has licensed LRRK2 inhibitor compounds from Genentech. These drug candidates may address the … was formerly at Genentech and led a study with co-authors from MJFF that found the company's LRRK2 inhibitors were … we announced that while the changes are seen in compounds from each company, they are reversible and not associated …
-
Building Enthusiasm for Movement Disorders Careers
April 6, 2017
… disease. Even though a good bit of time separates me from residency, I remember well how I came to the decision … who spanned all levels of neurology training, traveled from academic centers across the United States, Canada and Puerto Rico to hear lectures from internationally recognized movement disorder experts, …
-
Million Dollar Month: 2017 Wrap-Up
May 15, 2017
… Parkinson's Awareness Month . With new members joining in from around the globe and old friends returning with tried … and fun! Holly raised over $8,000 thanks to generous gifts from friends and a unique glass auction. Pancakes for … tee to benefit Team Fox. With the promotional support from their fellow YP markets--and an unexpected plug from …
-
"He Wanted a Cure to Be Part of His Legacy"
September 29, 2016
… Lynne and Brenda, their husbands and brother Gary (second from right). Photo courtesy of Sylvia Jacobs. Editor's Note: … he was determined that Parkinson's would not prevent him from going out or seeing the people he loved most. His … "He was clear about wanting to know where Parkinson's comes from and helping researchers get out there and cure this." …
-
miRNAs as new therapeutic targets and diagnostic biomarkers of PD
… Disease Consortium, we will first prepare total RNA samples from two brain regions, putamen and cortex, related to the PD and from the spinal fluid, cerebrospinal fluid (CSF) of PD … cerebrospinal fluid (CSF) that are significantly different from the miRNAs in the CSF of healthy controls as well as …
-
Exploring a Novel Pathogenetic Mechanism in Parkinson's Disease
… reported that neuropathological changes gradually propagate from Parkinson disease patients’ brains to grafted neurons. … We do not know how the abnormal proteins are transferred from host brain to graft cells. One hypothesis is that misfolded alpha-synuclein is transmitted from PD host cells to grafted neurons. Project Description: …