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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Outcome Measures, 2021
    Protective Effect of Immune Gene Subtype in Parkinson’s Disease

    Study Rationale: Our genetic studies of Parkinson’s disease (PD) have found a protective effect of an immune gene called HLA-DR, specifically the presence of the HLA-DRB1*04 subtype. We found that HLA...

  • Research Grant, 2021
    Changing Rhythms in Parkinson’s Disease: Development of Motor and Non-motor Markers of Progression Based on Continuous Daily Monitoring

    Study Rationale: Although new treatments are being developed to slow the progression of Parkinson’s disease (PD), assessing their effectiveness remains a challenge. Standard evaluations, conducted in...

  • Research Grant, 2021
    Gut Inflammation and Microbial Imbalance in Parkinson’s Disease

    Study Rationale: Studies show that the intestinal environment can affect the activity of the nervous system, and inflammation in the gut could contribute to the brain changes associated with Parkinson...

  • Therapeutic Pipeline Program, 2021
    Wireless “Nanoelectrodes” as a Minimally Invasive Alternative to Conventional Deep Brain Stimulation

    Study Rationale: Deep Brain Stimulation (DBS) has been used to ease motor symptoms in people with Parkinson’s disease (PD). This approach requires a surgical procedure to implant electrodes into the...

  • Research Grant, 2021
    Hidden Sorrows of Covid-19: Impact of Stress on Parkinson’s Disease Progression

    Study Rationale: People living with Parkinson’s disease (PD) are very sensitive to stress, which worsens motor symptoms (such as tremor) and leads to anxiety and depression. Studies in animals suggest...

  • Target Advancement Program, 2021
    Exploring How a Chemical Produced by Intestinal Microbes Contributes to the Pathology and Progression of Parkinson's Disease

    Study Rationale: Imbalances in the bacteria that inhabit the gut have been linked to the onset and progression of Parkinson’s disease (PD). However, the mechanisms by which an altered microbiome can...

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