The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
Research Grant, 2023Evaluation of a Digital Therapeutics (DTx) Mobile App and Algorithm for Personalized Medication and Treatment Plan Optimization for People with Parkinson’s Disease
Study Rationale: People with Parkinson’s disease (PD) have few options for keeping their symptoms under control. An app that could automatically monitor PD symptoms, like tremors, could allow users to...
Research Grant, 2022Restoring the Blood-brain Barrier to Prevent Dissemination of Alpha-synuclein and Progression of Parkinson’s Disease
Study Rationale: The cells of the brain are physically separated from the rest of the body by the blood-brain barrier, a network of blood vessels that restricts transfer of materials from the...
Research Grant, 2022Using the Emergence of New Symptoms as a Measure for Parkinson’s Disease Progression in Clinical Trials
Study Rationale: Studies suggest that as Parkinson’s disease (PD) progresses, new areas of the brain fall prey to PD pathology. If this is the case, PD progression may be best assessed by tracking the...
Summer 2022 RFP: Accelerating the Translation of Parkinson's Disease Therapies, 2022Validation of a Novel Mitochondrial Drug Target for Parkinson’s Disease
Study Rationale: Mitochondria provide cells with energy, but they also help regulate the flow of large amounts of calcium ions that flood neurons when they are active. In Parkinson’s disease (PD)...
Spring 2022 RFA: Target Advancement Program - Target Validation, 2022Evaluating an Insulin-degrading Enzyme as a Novel Therapeutic Target for Parkinson’s Disease
Study Rationale: In Parkinson’s disease (PD), the clumping of the protein alpha-synuclein in the brain causes the death of neurons. Recent studies have shown that the insulin-degrading enzyme (IDE)...
Research Grant, 2022Evaluation of a Monitoring System Based on a Wearable Sensor for Improving Swallowing and Saliva Control in Parkinson’s Disease
Study Rationale: Trouble with swallowing and increased drooling are common issues for people with Parkinson’s disease (PD). These oral symptoms occur in up to 80% of cases. Our prior work showed that...
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Our funding programs support basic, translational and clinical research from academia and industry.