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The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
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Previously funded studies appear chronologically, with the most recent appearing first.
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Data-Driven Subtyping and Stratification Program, 2023Identifying Proteomic Biomarkers for Monitoring the Progression of Parkinson’s Pathophysiology
Study Rationale: Parkinson’s disease (PD) is often diagnosed at a stage where the disease has progressed significantly, restricting treatment options and limiting the opportunity to understand how the...
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Circuits & Cellular Targets for PD’s Symptoms, 2023Pathophysiology of Neural Circuits Underlying Pain in Prodromal to Advanced Parkinson’s Disease
Study Rationale: Many people with Parkinson’s disease (PD) suffer from pain that is not managed well by existing therapies. We believe the ineffectiveness of these treatment strategies may be due to a...
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Translational Pipeline Program, 2023Evaluating Use of a Spinal Cord Prosthesis to Alleviate Locomotor Deficits in Parkinson’s Disease
Study Rationale: Over the past two decades, we have developed a therapy that restores walking after paralysis due to a spinal cord injury. This therapy uses an implanted neurostimulation prosthesis to...
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Aligning Science Across Parkinson's, 2023(Supplement) Exploring the Mechanisms by which Co-pathologies Drive Neuroinflammation and Progression in Parkinson’s Disease
Study Rationale: Although Parkinson’s disease (PD) is considered a synucleinopathy, the clinical progression of PD is driven by additional pathological proteins such as tau and beta amyloid. We...
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Accelerating Biological Understanding and Therapeutic Translation for Parkinson’s Disease Program, 2023Surviving on Borrowed Energy: Using Mitochondrial Transfer to Treat Parkinson’s Disease
Study Rationale: By the time the symptoms of Parkinson’s disease (PD) appear, many of the brain cells that produce the chemical dopamine have already died. This loss of dopamine-making cells leads to...
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Data-Driven Subtyping and Stratification Program, 2023Using Machine Learning on Longitudinal Data from Multiple Cohorts to Determine Biological Subtypes and Prediction Scores for Parkinson’s Disease
Study Rationale: We used to think of Parkinson's disease (PD) as a single disorder. However, individuals with PD can be very different in terms of their clinical characteristics and the biological...
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Our funding programs support basic, translational and clinical research from academia and industry.