Resources

MJFF Publications

The Michael J. Fox Foundation continually strives to communicate our scientific progress with the research community — through posters and presentations at meetings, in peer-reviewed scientific publications and with white paper reports.

Year Published

The Michael J. Fox Foundation’s Strategy to Generate, Characterize, and Distribute Preclinical Antibody Tools for Investigating Parkin/PINK1 and LRRK2- and PINK1-Related Rab Molecular Biology

November 17, 2017

A field-wide challenge in Parkinson’s disease (PD) research is a general lack of availability for high-quality, reproducible, and readily accessible preclinical research tools. To address these…

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User's guide for alpha-synuclein biomarker studies in biological fluids: Perianalytical considerations

July 22, 2017

This article summarizes perianalytical considerations for biomarker studies (based on immunoassays) in Parkinson's disease, with emphasis on quantifying total α-synuclein protein in biological fluids…

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The Michael J. Fox Foundation’s Strategy to Generate, Characterize, and Distribute Preclinical Alpha-Synuclein Research Tools for Molecular Biology

November 12, 2016

Mutations in the gene SNCA that encodes the protein alpha-synuclein as well as postmortem pathological studies strongly implicate a general role for alpha-synuclein in Parkinson’s disease (PD)…

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Phos-tag analysis of Rab10 phosphorylation by LRRK2: a powerful assay for assessing kinase function and inhibitors

July 29, 2016

Genta Ito, Kristina Katsemonova, Francesca Tonelli, Pawel Lis, Marco Baptista, Natalia Shpiro, Graham Duddy, Steve Wilson, Wing-Lok Ho, Shu-Leong Ho, Alastair D Reith, Dario R Alessi Autosomal…

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Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases

January 29, 2016

Martin Steger, Francesca Tonelli, Genta Ito, Paul Davies, Matthias Trost, Melanie Vetter, Stefanie Wachter, Esben Lorentzen, Graham Duddy, Stephen Wilson, Marco AS Baptista, Brian K Fiske, Matthew J…

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Histological and clinical pathology findings in LRRK2-related mouse and rat models

October 21, 2015

Terina N. Martinez1, Marco A.S. Baptista1, Melanie A. Greeley2, Mark T. Herberth2, Daniel Kovarik1, Adria Martig1, Kuldip D. Dave1,Mark A. Frasier1, Brian Fiske1, and Todd Sherer1Affiliations: The…

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Targeting GBA1 for Parkinson's disease research

October 21, 2015

Kuldip D. Dave1, Adria K. Martig1, Terina N. Martinez1, Lee J. Pellegrino2, Leo B. Dungan2, Rick Hamler2, Sean W. Clark2, Peter D. Buckett3, Yi Chen3, Weisong Shan3, Warren D. Hirst3, Michael Sasner4…

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Articles authored by Rachel Dolhun, MD, a movement disorder specialist on staff at MJFF, offer a practical review of topics related to Parkinson's disease for practicing clinicians.

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Breaking Research Updates

Read the latest developments in the field’s understanding and treatment of Parkinson’s disease.

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MJFF Publications

The Michael J. Fox Foundation’s Strategy to Generate, Characterize, and Distribute Preclinical Antibody Tools for Investigating Parkin/PINK1 and LRRK2- and PINK1-Related Rab Molecular Biology

User's guide for alpha-synuclein biomarker studies in biological fluids: Perianalytical considerations

The Michael J. Fox Foundation’s Strategy to Generate, Characterize, and Distribute Preclinical Alpha-Synuclein Research Tools for Molecular Biology

Phos-tag analysis of Rab10 phosphorylation by LRRK2: a powerful assay for assessing kinase function and inhibitors

Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases

Histological and clinical pathology findings in LRRK2-related mouse and rat models

Targeting GBA1 for Parkinson's disease research

Breaking Research Updates