Choosing the Appropriate Funding Program
MJFF invites investigators to carefully consider the stage of their particular project and choose the program that best fits the critical next step objectives of their particular research. Applicants should NOT submit the same idea to multiple programs. Projects submitted to a program that are deemed by MJFF staff to be more appropriate for a different program may at MJFF discretion be moved into another program for funding consideration.
Indirect Policy and General Funding Information
As one laboratory group may not possess the expertise in all steps of a particular project, collaborations are strongly encouraged for all proposals submitted to the MJFF. This is especially important for applicants seeking to use specific reagents or tools-including animal models of PD-for which the applicant has limited previous experience. Inability to develop or use tools proposed for a particular awarded project can lead to delay of funding and possible award termination.
Inclusion of Pharmacokinetic Information, Brain Penetration Data and Dosing Rationale
Overlap of Proposed Projects with Existing MJFF Awards
Applicants should review the specific submission instructions for each program provided on the MJFF website. Programs can either require a one or two stage submission process. When there are two stages to the MJFF review process: a 'Pre-Proposal' stage and a 'Full Proposal' stage. Note that the application, pre-proposal, and full proposal requirements for each program may differ and applicants should carefully review instructions for details, including use of required proposal templates.
All submissions undergo an administrative and scientific review, which also considers overall funder priorities. Submitting companies will also undergo a general evaluation to assess financial and overall company health.
General Review Criteria
Clinical Research Projects Criteria
MJFF treats all Pre-Proposals, Applications, research projects and associated research information (collectively, the "Confidential Information") in confidence using no less than reasonable care in protecting such Confidential Information from disclosure to third parties who do not participate in the grant review process and MJFF assessments. All Confidential Information will be used by MJFF and its grant reviewers only internally for the purposes of reviews and assessments, and will be shared only in accordance with its sharing policy stated herein. Notwithstanding MJFF's and its reviewers' obligations regarding such Confidential Information, such obligations cover any information retained in their unaided memories and may not be used without the permission of the disclosing party. Notwithstanding the foregoing, the obligations governing the disclosure and use of Confidential Information do not apply with respect to Confidential Information that it can be demonstrated:
- was generally known to the public prior to the effective date of this RFA; or
- becomes generally known to the public through no unlawful or unauthorized act of omission by any recipient of Confidential Information, or in violation of this RFA; or
- was independently developed by any recipient prior to the effective date of this RFA; or
- was disclosed to a recipient by a third party who has the right to make such disclosure.
If any recipient of Confidential Information is requested to produce any of the Confidential Information pursuant to a legal or governmental proceeding, such recipient shall give the applicant or other owner of such Confidential Information (the "Discloser") as much prior notice of such requirement as is reasonably practicable under the circumstances and shall use its reasonable efforts to assist the Discloser of such Confidential Information in objecting to such request. If a recipient is compelled to disclose any of the Confidential Information pursuant to such legal or governmental proceeding, such recipient shall use its reasonable efforts to assist Discloser in obtaining confidential treatment for such Confidential Information, will disclose only that portion of the Confidential Information which is responsive to the order, and will provide the Discloser with any copies of Confidential Information so disclosed; provided that such Confidential Information shall remain confidential until it falls into one of the categories specified in this Section entitled "CONFIDENTIALITY."
Principal investigators and their paid collaborators submitting applications to the RFA will be excluded from serving on the GRC that reviews their grant. However, non-applicants who are invited to serve on the GRC may still have a conflict of interest that arises during the grant review process. A GRC member is judged to have a conflict of interest if (1) he or she is a collaborator, sub-contractor, and/or consultant with an investigator that has a grant application before the GRC, (2) the application is from the reviewer's own institution regardless of whether or not reviewer has had any involvement in preparing the application, (3) the member, his/her immediate family, or close professional associate(s) has a financial or vested interest in the outcome of the proposed research (even if no significant involvement is apparent in the proposal being considered), or (4) the GRC member has been involved in discussions regarding the application, is a provider of services, cell lines, reagents, or other materials, or writer of a letter of reference for the applicant.
When a conflict of interest is deemed to be present, the GRC member will be ineligible to review the proposal and will be asked to leave the room when the proposal is discussed during the review process, including when it is scored. Nor will the results of the review be made known to the conflicted reviewer until after the entire review process is complete. GRC members are also urged to avoid any actions that might give the appearance that a conflict of interest exists, even though he or she believes there may not be an actual conflict of interest.
MJFF's role in grants awarded through MJFF funding opportunities is that of a funder; MJFF cannot be considered the sponsor of funded projects. As such, MJFF will not assume any liability associated with funded projects. Applicants who are ultimately awarded in these programs will be required to sign an award agreement that releases MJFF from liability.
As MJFF is a public charity, research conducted with funds from MJFF (the "Research") must be conducted in the public interest. MJFF acknowledges that any discoveries and related regulatory approvals made by researchers through the Research are the property of those conducting and responsible for the Research and that unless otherwise agreed to by the parties, such researchers have the first opportunity to exploit the Research commercially or otherwise. Notwithstanding, each Applicant acknowledges that MJFF has the right, after reasonable consultation which will not be unreasonably denied, conditioned or delayed, to release a summary of findings of the Research within 3 months from the date of the grant program expiration.
Notwithstanding the foregoing, MJFF requires that all tools or reagents (i) funded by and (ii) that result from awarded projects (collectively, the "Results") be made readily available to the community including MJFF for research purposes. You will be required to agree that you will cooperate and collaborate with MJFF and other researchers and share access to Results on fair and reasonable terms and conditions within 3 months of grant expiration. By submitting your application, you and your institution are confirming that you are not aware of any requirements that would prohibit, delay, or restrict your ability to share your Results from this initiative, including requirements of third-party collaborators or companies with which you are affiliated.
Intellectual Property Agreements among Collaborators
Although MJFF does not specify when intellectual property (IP) negotiations must take place among researchers funded under this program, MJFF does require that collaborators agree on any material IP issues prior to submission of final applications. Applications that do not include a letter indicating that IP matters have been discussed will not be reviewed.
Clinical Trial Registration
MJFF requires that any clinical trial awarded under any of its funding programs be registered with FoxTrialFinder.org, Clinicaltrials.gov, PDTrials.org, or other appropriate public registry.
Results of the Research will be published as rapidly as possible in the open scientific literature, consistent with high standards of scientific excellence and rigor, and include acknowledgement of the funding provided by The Michael J. Fox Foundation for Parkinson's Research.
Requirements for Grantees
- Progress Reports. Progress reports are due every six months or at other times as deemed necessary by MJFF for project evaluation. Progress report forms will be provided by MJFF approximately two months before they are due.
- Assessment Meeting. Principal investigators on funded grants are required to attend assessment meetings in-person at the midpoint and completion of their project at which they will report on the progress of their projects, exchange information with other investigators, explore possible collaborative efforts among grantees, and identify resources that would enhance the productivity of the grantees or the field-at-large.
- Financial Accountability. Grantees are expected to account for the moneys expended under any MJFF grant; any moneys spent either not in accordance with the approved research project or prior to pre-approval of any material change in your project are both (i) recoverable by, and subject to restitution by you, to MJFF and (ii) may be cause for immediate termination of funding by MJFF.
Grantees are expected to meet scheduled milestones and deliver deliverables on time, and failure to meet milestones, furnish scheduled deliverables, including any reports, or to comply with the terms of the grant may serve as one or more bases for termination of funding by MJFF. Additionally, progress reports must be favorably reviewed by an MJFF-appointed Assessment Committee against MJFF Assessment Criteria if funding is to continue. The assessment meeting will occur at the completion of the award. Travel expenses will be provided by MJFF and should not be included in the application budget.
While we encourage awardees to seek additional funds to further their work once the term of the initial award has expired, MJFF has no guaranteed policy for continuation of grants. MJFF may, at its discretion, seek to further support clearly successful projects. Awardees are also eligible to apply for funding under another MJFF RFA.
MJFF welcomes the opportunity to clarify any issues or questions from potential applicants regarding any MJFF funding program. To avoid submission complications, MJFF encourages questions well in advance of the submission deadlines. Please direct inquiries regarding programmatic, fiscal and administrative issues to email@example.com.