The Foundation supports research that can lead to the creation of better Parkinson's treatments. Here you can search previously awarded grants by keyword, program name, researcher name, institution or organization name and/or year.
FUNDED GRANTS ( 125)
Improved Biomarkers & Clinical Outcome Measures, 2017
MicroRNAs (miRs) are short RNA molecules (messengers that carry genetic information to DNA) that block protein expression by crossing with hundreds of mRNA targets. Neuron-restricted miRs regulate specific aspects of neuron development and function, unlike broadly expressed miRs that control house-keeping processes. Deregulation of neuron miR expression leads to brain dysfunction....
Research Grant, 2017
Drawing on the Parkinson's Progression Markers Initiative (PPMI) Data to Link Changes in the PINK1/Parkin Genes with Parkinson's Disease
Two proteins, PINK1 and Parkin, prevent cell death by breaking down damaged mitochondria, cell's energy generators. This process is known as mitophagy. Mutations in PINK1/Parkin genes -- genetic changes that render these proteins unable to perform their function -- cause Parkinson's disease (PD). Failure to remove damaged mitochondria from the cell can start or speed up the course...
Research Grant, 2017
The GBA gene is responsible for the production of beta-glucocerebrosidase, an enzyme that breaks down fats. Scientists are starting to recognize changes, or mutations, in the GBA gene as a previously unknown cause of some Parkinson's disease (PD) cases. Many healthy people also have a mutation in this gene but do not go on to develop PD. Mutations in this gene that make the enzyme...
LRRK2 Therapeutic and Safety Initiative, 2017
Recent studies have shown that mutations in the LRRK2 gene, known to increase the risk of Parkinson's disease (PD), are also associated with inflammatory bowel disease (IBD), a chronic disorder of the gut characterized by recurrent abdominal pain, diarrhea, rectal bleeding and weight loss. Subsequently, IBD patients have been found to be at a higher risk of developing PD compared ...
Researchers: Inga Peter, PhD
Computational Science 2017, 2017
Because Parkinson's disease (PD) affects people around the world regardless of their ethnicity or place of residence, research to find a cure for Parkinson's is truly an international effort. We aim to support this effort by creating the largest international database of brain images from people with and without PD. We will search these images for variations in the brains of peopl...
Researchers: Neda Jahanshad, PhD