The Foundation supports research that can lead to the creation of better Parkinson's treatments. Here you can search previously awarded grants by keyword, program name, researcher name, institution or organization name and/or year.
FUNDED GRANTS ( 25)
Access to Data and Biospecimens, 2018
Uric acid is a chemical produced naturally in the human body. In this project, we aim to investigate whether uric acid is an antioxidant capable of reducing the risk of Parkinson's disease (PD), and in particular, its inherited form caused by a change -- mutation -- in the gene for leucine-rich repeat kinase 2 (LRRK2), the greatest known genetic contributor to PD. In this study...
Researchers: Rachit Bakshi, PhD
Research Grant, 2018
As wearable technology -- smartphones and wearable devices with built-in sensors -- became increasingly more common, affordable and effective, its use in the evaluation and treatment of Parkinson's disease (PD) has advanced rapidly. Such technology can collect data on mobility, symptom intensity and medication effects. While useful, these devices have limitations: They must be wor...
Researchers: Dina Katabi, PhD, MS, BS
Therapeutic Pipeline Program, 2018
Alpha-synuclein is a sticky protein that clumps in the brains of people with Parkinson's disease (PD). Duplication or triplication of SNCA, a gene responsible for the production of alpha-synuclein, leads to inherited PD. Additional copies of SNCA produce excess of alpha-synuclein, promoting neurodegeneration and increasing the severity of Parkinson's symptoms. We propose to limit ...
Researchers: Jack T. Rogers, PhD
Computational Science, 2017
To test this hypothesis, we will employ recent discoveries in computer science, PD biomarker research and standardized sets of PD data. First, we will develop machine-learning techniques to analyze multimodal data from people with and without Parkinson's. Results will help identify whether someone does or does not have PD, and they will be grouped accordingly. Second, we will confirm ...
Researchers: Wasim Q. Malik, PhD
Improved Biomarkers and Clinical Outcome Measures, 2015
Current methods to evaluate motor impairments in Parkinson's disease rely on subjective examinations. Our team seeks to develop an objective assessment of motor deficits by monitoring natural interactions with a keyboard (on a computer or smart device). This approach provides a window to how the brain behaves during typical daily use of these devices (e.g. writin...
Researchers: Martha L. Gray, PhD