The Foundation supports research that can lead to the creation of better Parkinson's treatments. Here you can search previously awarded grants by keyword, program name, researcher name, institution or organization name and/or year.
FUNDED GRANTS ( 19)
Research Grant, 2017
The RESISTA-PD trial - The Effects of Resistant Starch on Bowel Habits, Short Chain Fatty Acids and Gut Microbiota in Parkinson Disease
Individuals with Parkinson's disease (PD) frequently suffer from constipation; those with PD also have altered bacterial composition in the gut. The RESISTA-PD trial investigates whether daily intake of a dietary supplement (resistant starch, provided as a water-soluble powder) can change gut bacteria composition and whether this supplement can improve bowel habits.
Researchers: Marcus M. Unger, MD
Research Grant, 2017
Gastrointestinal (GI) symptoms, such as constipation, nausea and vomiting, are common in Parkinson's disease (PD), but the cause of these symptoms is not entirely clear. Slow movement of food through the stomach, intestine and colon is one possibility. We will test it by measuring the speed with which food moves through these regions of the GI tract in people with and without PD. ...
Researchers: William L. Hasler, MD
Therapeutic Pipeline Program, 2015
Constipation and gastroparesis (slow stomach emptying) are common non-motor symptoms of Parkinson's disease (PD). These symptoms cause troublesome gastrointestinal issues and can impair the absorption of and, response to, Parkinson's medications, such as levodopa. Unfortunately, there are FDA-approved treatments for slow stomach emptying in PD, and rigorously te...
Researchers: Leslie Jameleh Cloud, MD, MSc
Therapeutic Pipeline Program, 2013
The purpose of this study, called MOVE-PD, is to investigate how patients with Parkinson's disease (PD) and chronic constipation respond to the drug RM-131. The study will evaluate the safety and tolerability of the drug and evaluate whether RM-131 relieves constipation and related uncomfortable abdominal symptoms in patients who are unsatisfied with other therapie...
Researchers: Keith Gottesdiener, MD
Rapid Response Innovation Awards, 2012
The cause of Parkinson's disease is unknown and a reliable biomarker to identify Parkinson's disease patients as early as possible is urgently needed. Nerve cells near the nose and in the gut become first affected in Parkinson's disease and patients frequently suffer from loss of smell and constipation. The nose and gut harbor very high amounts of bacteria that influence our b...