The Foundation supports research that can lead to the creation of better Parkinson's treatments. Here you can search previously awarded grants by keyword, program name, researcher name, institution or organization name and/or year.
FUNDED GRANTS ( 426)
LRRK2 Biology Consortium, 2018
Parkinson's disease (PD) affects nearly any body system, as evidenced by the diversity of its symptoms. While its non-motor symptoms, such as olfactory dysfunction, rapid eye movement sleep behavior disorder (RBD) and gastrointestinal (GI) abnormalities, do not define the disease, they have a large impact on those living with it. In this project, we will use a pre-clinical model o...
Researchers: R. Jeremy Nichols, PhD
Computational Science, 2018
Clinical research as well as wearable devices and phone apps used by people with Parkinson's disease (PD) generate large volumes of data, such as genetic and imaging data and data on motor symptoms. The extreme complexity and volume of this data call for new, efficient computer analysis methods.
Neural-network-based learning is a programming approach inspired by the rema...
Access to Data and Biospecimens, 2018
Uric acid is a chemical produced naturally in the human body. In this project, we aim to investigate whether uric acid is an antioxidant capable of reducing the risk of Parkinson's disease (PD), and in particular, its inherited form caused by a change -- mutation -- in the gene for leucine-rich repeat kinase 2 (LRRK2), the greatest known genetic contributor to PD. In this study...
Researchers: Rachit Bakshi, PhD
Research Grant, 2018
Two proteins, PINK1 and parkin, keep cells healthy by breaking down damaged mitochondria, cell's energy generators. This process is known as mitophagy or mitochondrial self-eating. Mutations -- genetic changes -- in PRKN and PINK1 disrupt this process and cause Parkinson's disease (PD). We have developed not only a detailed understanding of these proteins' functions but also metho...
Researchers: J. Wade Harper, PhD
Research Grant, 2018
This study aims to produce data that will help to understand the molecular processes and networks underlying Parkinson's disease (PD). In this study, we will use cells from people who participated in the Parkinson's Progression Markers Initiative (PPMI), our large-scale, international biomarker study.
Research approaches including complex genetics will generate critica...
Researchers: Andrew B. Singleton, PhD