The Foundation supports research that can lead to the creation of better Parkinson's treatments. Here you can search previously awarded grants by keyword, program name, researcher name, institution or organization name and/or year.
FUNDED GRANTS ( 408)
Therapeutic Pipeline Program, 2017
The notion of misfolded alpha-synuclein (alpha-syn) aggregates moving from neuron-to-neuron is a mechanism that is gaining widespread acceptance as a central mechanism in the development of Parkinson's disease. Therapies designed to stop this spreading point towards a novel therapeutic route for preventing the development of Parkinson's disease.
With the development of...
Improved Biomarkers and Clinical Outcome Measures, 2017
Recent reports of "super-smelling powers" published in The Lancet Neurology has triggered the idea of a specific "musky" scent in the sebum, an oily skin secretion, of those with Parkinson's disease (PD), providing a novel basis for PD biomarker (tracks disease activity) research. Our customizable MouSensor technology allows creation of highly sensitive biosensors for specific odo...
Research Grant, 2017
The contribution of inflammation to Parkinson's disease (PD) is increasingly being recognized. However, the stage of the disease in which inflammation is prevalent and/or important remains unclear. Our recent work suggests that inflammation may be increased early in the course of PD.
We aim to replicate our previous findings and demonstrate that a panel of inflammat...
Researchers: Nicolas Dzamko, PhD
LRRK2 Biology Consortium, 2017
Development of Nanobodies as Novel Tools to Characterize LRRK2 as a Potential Drug Target for Parkinson's Disease
Several genes play a crucial role in Parkinson's disease (PD). The most common genetic cause of PD is mutations in the gene encoding LRRK2, a very large and complex protein with different enzyme (accelerates chemical reactions) functions. Targeting the multiple enzymatic functions of LRRK2 represents a very attractive approach for designing novel therapeutics for PD that requires ...
Research Grant, 2017
Parkinson's disease (PD) is characterized by impairment of motor control as a result from extensive neuron death. The primary mechanism responsible for the progressive neuronal loss in PD remains unknown; however, clues have been obtained from families who have a genetic form of PD that is accompanied by a mutation (change in genetic material, or DNA) in an important protein called...
Researchers: Claudio Hetz Flores, PhD