Birgitt Schüle, MD
Assistant Professor at The Parkinson’s Institute
Location: Sunnyvale, California, United States
Birgitt Schüle, MD, studied medicine at the Georg-August University, Göttingen and Medical University Lübeck, Germany from 1993-2001. She received her doctoral degree for her medical thesis in neurophysiology from the Georg-August University, Göttingen. Dr. Schüle worked during her neurological internship (2001-2002) at the Medical University Lübeck with Dr. Christine Klein on genetic forms of PD and dystonia. From 2003-2005, Dr. Schüle completed a postdoctoral fellowship in the laboratory of Dr. Uta Francke, Stanford University, before joining the Parkinson’s Institute in late 2005.
Dr. Schüle heads the neurogenetics program, which includes clinical genetic studies of families and sporadic cases with parkinsonism. Since 2008, she has built a stem cell program developing novel “disease in-a-dish” models of Parkinson’s disease using patient-derived induced pluripotent stem cells. Stem cell-derived neurons are representing a new human cellular model for studying disease mechanisms and the effects of environmental toxicants, and for developing new strategies of innovative drug discovery.
- Genetic Validation of a New Causative Gene for Familial and Sporadic Parkinson’s Disease (2013)
- Parkinson’s Institute LRRK2 Cohort: Clinical Phenotype, Pre/Non-Motor and Environmental Risk Assessment (2012)
- Increasing the Sensitivity of LRRK2 Assays: Development of Proximity Ligation Assays for LRRK2 (2011)
- DNA Methylation as an Epigenetic Mechanism in the Etiopathogenesis of Parkinson's Disease (2008)