The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
-
Research Grant, 2018pS65-Ub as a Biomarker for Parkinson's Disease
Study Rationale:
The PINK1 and parkin proteins jointly ensure quality control of mitochondria, the cell's powerhouse. Together they modify damaged mitochondria with phosphorylated ubiquitin (pS65-Ub)... -
Research Grant, 2018Exploring the Effect of Altitude on Parkinson's Disease
Study Rationale:
There is a lot of anecdotal evidence that the symptoms of Parkinson's disease (PD) may improve markedly during visits to high-altitude destinations. Given the significant, but as yet... -
Research Grant, 2018URMC-099 in an In Vivo AAV-hSYN Model of Parkinson’s Disease
Study Rationale:
Parkinson's disease (PD) can be modeled by over-expressing human synuclein, a protein that can clump together to disrupt normal signaling in dopamine-containing neurons, which in turn... -
Research Grant, 2018LRRK2-Mediated Rab Protein Phosphorylation in Monocytes and Neutrophils in Parkinson's Disease
Study Rationale:
Mutations in the LRRK2 gene cause some forms of Parkinson's disease. Studying this gene's effects has provided insight into the physiological processes that lead to genetic and... -
Research Grant, 2018Feasibility of Screening for Parkinson's Genetic Risk Factors in People of Asian Ancestry
Study Rationale:
Mutations in the LRRK2 gene can cause Parkinson's disease (PD), and therapies against associated dysfunction in the LRRK2 protein are in clinical trials. A specific variant of the... -
Research Grant, 2018Analysis of the LRRK2-Rab Signaling Pathway
Promising Outcomes of Original Grant:
The highlight of our teams' recent MJFF funded research has been the discovery of the key physiological targets of LRRK2 that comprise a group of proteins termed...
Apply for a Grant
Our funding programs support basic, translational and clinical research from academia and industry.