Neurotrophic Factors PRIORITY AREA
Why Are Neurotrophic Factors a Priority?
Neurotrophic factors are specialized proteins that are essential for developing and maintaining healthy neurons. Pre-clinical studies and several early phase clinical trials have shown the potential of neurotrophic factor therapy for people with Parkinson's disease. However, no neurotrophic factor therapy has yet demonstrated sufficient safety and efficacy in humans. The Foundation considers the development of neurotrophic factors one of the most promising strategies in developing a disease-modifying therapy for Parkinson's patients.
Our Investment in Neurotrophic Factors Research
The Michael J. Fox Foundation has supported several efforts to develop neurotrophic factor therapies, ranging from proof-of-concept studies to clinical testing. Additionally, the Foundation has supported pre-clinical studies of novel neurotrophic factors and of ways to improve delivery of these factors to the brain.
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