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  • Autophagy in neurodegenerative disorders: pathogenic roles and therapeutic implications
    2010
    RESTRICTED
    Title: Autophagy in neurodegenerative disorders: pathogenic roles and therapeutic implications
    Author(s): Rebecca Banerjee, M. Flint Beal, Bobby Thomas
    Journal Name: Trends in Neurosciences
    Publisher: Elsevier BV
    Vol: 33
    Issue #: 12
    Start Page: 541
    End Page: 549
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.tins.2010.09.001
    Best OA location URL: https://europepmc.org/articles/pmc2981680?pdf=render
    Citation Count: 190
  • Characterization of axon guidance cue sensitivity of human embryonic stem cell-derived dopaminergic neurons
    2010
    RESTRICTED
    Title: Characterization of axon guidance cue sensitivity of human embryonic stem cell-derived dopaminergic neurons
    Author(s): Branden Cord, Jie Li, Melissa Works, Susan K. McConnell, Theo D. Palmer, Mary Hynes
    Journal Name: Molecular and Cellular Neuroscience
    Publisher: Elsevier BV
    Vol: 45
    Issue #: 4
    Start Page: 324
    End Page: 334
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.mcn.2010.07.004
    Best OA location URL:
    Citation Count: 20
  • Genetic variation of the mitochondrial complex I subunit NDUFV2 and Parkinson’s disease
    2010
    RESTRICTED
    Title: Genetic variation of the mitochondrial complex I subunit NDUFV2 and Parkinson’s disease
    Author(s): Kenya Nishioka, Carles Vilariño‐Güell, Stephanie A. Cobb, Jennifer M. Kachergus, Owen A. Ross, Emna Hentati, Fayçal Hentati, Matthew J. Farrer
    Journal Name: Parkinsonism & Related Disorders
    Publisher: Elsevier BV
    Vol: 16
    Issue #: 10
    Start Page: 686
    End Page: 687
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.parkreldis.2010.09.007
    Best OA location URL: https://europepmc.org/articles/pmc4381965?pdf=render
    Citation Count: 37
  • Impaired dopaminergic neurotransmission and microtubule-associated protein tau alterations in human LRRK2 transgenic mice
    2010
    RESTRICTED
    Title: Impaired dopaminergic neurotransmission and microtubule-associated protein tau alterations in human LRRK2 transgenic mice
    Author(s): Heather L. Melrose, Justus C. Dächsel, Bahareh Behrouz, Sarah Lincoln, Mei Yue, Kelly M. Hinkle, Caroline Kent, Elena Korvatska, Julie P. Taylor, Louise Witten, Yideng Liang, Joel E. Beevers, Mona Boules, Brittany N. Dugger, Vanida A. Serna, A. Gaukhman, Xin Yu, Monica Castanedes‐Casey, Adam Braithwaite, Sina Ogholikhan, Naisen Yu, D.I. Bass, G. Tyndall, Gerard D. Schellenberg, Dennis W. Dickson, Christopher Janus, Matthew J. Farrer
    Journal Name: Neurobiology of Disease
    Publisher: Elsevier BV
    Vol: 40
    Issue #: 3
    Start Page: 503
    End Page: 517
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.nbd.2010.07.010
    Best OA location URL: https://europepmc.org/articles/pmc2955774?pdf=render
    Citation Count: 242
  • Molecular Chaperones as Rational Drug Targets for Parkinsons Disease Therapeutics
    2010
    RESTRICTED
    Title: Molecular Chaperones as Rational Drug Targets for Parkinsons Disease Therapeutics
    Author(s): Suneil K. Kalia, Lorraine V. Kalia, Pamela J. McLean
    Journal Name: CNS & Neurological Disorders - Drug Targets
    Publisher: Bentham Science Publishers Ltd.
    Vol: 9
    Issue #: 6
    Start Page: 741
    End Page: 753
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.2174/187152710793237386
    Best OA location URL: https://europepmc.org/articles/pmc3364514?pdf=render
    Citation Count: 92
  • Using Voluntary Cough To Detect Penetration and Aspiration During Oropharyngeal Swallowing in Patients With Parkinson Disease
    2010
    RESTRICTED
    Title: Using Voluntary Cough To Detect Penetration and Aspiration During Oropharyngeal Swallowing in Patients With Parkinson Disease
    Author(s): Teresa Pitts, Michelle S. Troche, Giselle Mann, John C. Rosenbek, Michael S. Okun, Christine M. Sapienza
    Journal Name: Chest
    Publisher: Elsevier BV
    Vol: 138
    Issue #: 6
    Start Page: 1426
    End Page: 1431
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1378/chest.10-0342
    Best OA location URL:
    Citation Count: 77
  • N‐acetylcysteine prevents loss of dopaminergic neurons in the EAAC1−/− mouse
    2010
    RESTRICTED
    Title: N‐acetylcysteine prevents loss of dopaminergic neurons in the EAAC1−/− mouse
    Author(s): Ari Berman, Wai Yee Chan, Angela Brennan, Reno C. Reyes, Brittany Adler, Sang Won Suh, Tiina M. Kauppinen, Ylva Edling, Raymond A. Swanson
    Journal Name: Annals of Neurology
    Publisher: Wiley
    Vol: 69
    Issue #: 3
    Start Page: 509
    End Page: 520
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1002/ana.22162
    Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ana.22162
    Citation Count: 122
  • Bioactivity of AAV2‐neurturin gene therapy (CERE‐120): Differences between Parkinson's disease and nonhuman primate brains
    2010
    RESTRICTED
    Title: Bioactivity of AAV2‐neurturin gene therapy (CERE‐120): Differences between Parkinson's disease and nonhuman primate brains
    Author(s): Raymond T. Bartus, Christopher R. Herzog, Yaping Chu, Alistair Wilson, Lamar Brown, João Siffert, Eugene M. Johnson, C. Warren Olanow, Elliott J. Mufson, Jeffrey H. Kordower
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 26
    Issue #: 1
    Start Page: 27
    End Page: 36
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1002/mds.23442
    Best OA location URL: https://europepmc.org/articles/pmc6333467?pdf=render
    Citation Count: 148
  • HCN channelopathy in external globus pallidus neurons in models of Parkinson's disease
    2010
    RESTRICTED
    Title: HCN channelopathy in external globus pallidus neurons in models of Parkinson's disease
    Author(s): C. Savio Chan, Kelly E. Glajch, Tracy S. Gertler, Josefina Guzmán, Jeff Mercer, Alan S. Lewis, Alan B Goldberg, Tatiana Tkatch, Ryuichi Shigemoto, Sheila M. Fleming, Dane M. Chetkovich, Pavel Osten, Hitoshi Kita, D. James Surmeier
    Journal Name: Nature Neuroscience
    Publisher: Springer Science and Business Media LLC
    Vol: 14
    Issue #: 1
    Start Page: 85
    End Page: 92
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1038/nn.2692
    Best OA location URL: https://europepmc.org/articles/pmc3058391?pdf=render
    Citation Count: 166
  • Decreased glutamic acid decarboxylase mRNA expression in prefrontal cortex in Parkinson's disease
    2010
    RESTRICTED
    Title: Decreased glutamic acid decarboxylase mRNA expression in prefrontal cortex in Parkinson's disease
    Author(s): Amélie C. Lanoue, Alexandra Dumitriu, Richard H. Myers, Jean‐Jacques Soghomonian
    Journal Name: Experimental Neurology
    Publisher: Elsevier BV
    Vol: 226
    Issue #: 1
    Start Page: 207
    End Page: 217
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.expneurol.2010.09.001
    Best OA location URL: https://europepmc.org/articles/pmc3108022?pdf=render
    Citation Count: 46
  • Qualitative Imaging of Adeno-Associated Virus Serotype 2–Human Aromatic L-Amino Acid Decarboxylase Gene Therapy in a Phase I Study for the Treatment of Parkinson Disease
    2010
    RESTRICTED
    Title: Qualitative Imaging of Adeno-Associated Virus Serotype 2–Human Aromatic L-Amino Acid Decarboxylase Gene Therapy in a Phase I Study for the Treatment of Parkinson Disease
    Author(s): Francisco Valles, Massimo S. Fiandaca, Jamie L. Eberling, Philip A. Starr, Paul Larson, Chadwick W. Christine, John Forsayeth, R. Mark Richardson, Xiaomin Su, Michael J. Aminoff, Krystof S. Bankiewicz
    Journal Name: Neurosurgery
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Vol: 67
    Issue #: 5
    Start Page: 1377
    End Page: 1385
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1227/neu.0b013e3181f53a5c
    Best OA location URL:
    Citation Count: 56
  • SNCA Variant Associated With Parkinson Disease and Plasma α-Synuclein Level
    2010
    RESTRICTED
    Title: SNCA Variant Associated With Parkinson Disease and Plasma α-Synuclein Level
    Author(s): Ignacio Mata, Min Shi, Pinky Agarwal, Kathryn A. Chung, Karen L. Edwards, Stewart A. Factor, Douglas Galasko, Carmen Ginghină, Alida Griffith, Donald S. Higgins, Denise M. Kay, Hojoong Kim, James B. Leverenz, Joseph F. Quinn, John W. Roberts, Ali Samii, Katherine W. Snapinn, Debby W. Tsuang, Dora Yearout, Jing Zhang, Haydeh Payami, Cyrus P. Zabetian
    Journal Name: Archives of Neurology
    Publisher: American Medical Association (AMA)
    Vol: 67
    Issue #: 11
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1001/archneurol.2010.279
    Best OA location URL: https://europepmc.org/articles/pmc3010848?pdf=render
    Citation Count: 147
  • CD3 in Lewy pathology: does the abnormal recall of neurodevelopmental processes underlie Parkinson’s disease
    2010
    RESTRICTED
    Title: CD3 in Lewy pathology: does the abnormal recall of neurodevelopmental processes underlie Parkinson’s disease
    Author(s): Rudy J. Castellani, Summer L. Nugent, Alan L. Morrison, Xiongwei Zhu, Hyoung Gon Lee, Peggy L.R. Harris, Vladan Bajić, Hari Shanker Sharma, Shu G. Chen, Peter Oettgen, George Perry, Mark A. Smith
    Journal Name: Journal of Neural Transmission
    Publisher: Springer Science and Business Media LLC
    Vol: 118
    Issue #: 1
    Start Page: 23
    End Page: 26
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1007/s00702-010-0485-5
    Best OA location URL: https://europepmc.org/articles/pmc3090073?pdf=render
    Citation Count: 12
  • Why Do We Need Multifunctional Neuroprotective and Neurorestorative Drugs for Parkinson’s and Alzheimer’s Disorders?
    2010
    RESTRICTED
    Title: Why Do We Need Multifunctional Neuroprotective and Neurorestorative Drugs for Parkinson’s and Alzheimer’s Disorders?
    Author(s): Moussa B. H. Youdim
    Journal Name: Rambam Maimonides Medical Journal
    Publisher: Rambam Health Corporation
    Vol: 1
    Issue #: 2
    Start Page: e0011
    End Page: e0011
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License: cc-by
    DOI - Digital Object Identifier: 10.5041/rmmj.10011
    Best OA location URL: https://www.rmmj.org.il/userimages/13/0/PublishFiles/13Article.pdf
    Citation Count: 8
  • PGC-1 α, A Potential Therapeutic Target for Early Intervention in Parkinson’s Disease
    2010
    RESTRICTED
    Title: PGC-1 α, A Potential Therapeutic Target for Early Intervention in Parkinson’s Disease
    Author(s): Bin Zheng, Zhixiang Liao, Joseph J. Locascio, Kristen A. Lesniak, Sarah S. Roderick, Marla L. Watt, Aron C. Eklund, Yanli Zhang‐James, Peter D. Kim, Michael A. Hauser, Edna Grünblatt, Linda Moran, Silvia Mandel, Peter Riederer, Renee M. Miller, Howard J. Federoff, Ullrich Wüllner, Spyridon Papapetropoulos, Moussa B. H. Youdim, Ippolita Cantuti-Castelvetri, Anne B. Young, Jeffery M. Vance, Richard L. Davis, John C. Hedreen, Charles H. Adler, Thomas G. Beach, Manuel B. Graeber, Frank A. Middleton, Jean‐Christophe Rochet, Clemens R. Scherzer
    Journal Name: Science Translational Medicine
    Publisher: American Association for the Advancement of Science (AAAS)
    Vol: 2
    Issue #: 52
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1126/scitranslmed.3001059
    Best OA location URL: https://europepmc.org/articles/pmc3129986?pdf=render
    Citation Count: 695
  • A subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptors
    2010
    RESTRICTED
    Title: A subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptors
    Author(s): Praseeda Mullasseril, Kasper B. Hansen, Katie M. Vance, Kevin K. Ogden, Hongjie Yuan, Natalie L. Kurtkaya, Rose M Santangelo, Anna G. Orr, Phuong Le, Kimberly Vellano, Dennis Liotta, Stephen F. Traynelis
    Journal Name: Nature Communications
    Publisher: Springer Science and Business Media LLC
    Vol: 1
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1038/ncomms1085
    Best OA location URL: https://www.nature.com/articles/ncomms1085.pdf
    Citation Count: 139
  • Biomarkers in Parkinson’s disease: a funder’s perspective
    2010
    RESTRICTED
    Title: Biomarkers in Parkinson’s disease: a funder’s perspective
    Author(s): Mark Frasier, Sohini Chowdhury, Jamie L. Eberling, Todd Sherer
    Journal Name: Biomarkers in Medicine
    Publisher: Informa UK Limited
    Vol: 4
    Issue #: 5
    Start Page: 723
    End Page: 729
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.2217/bmm.10.89
    Best OA location URL:
    Citation Count: 15
  • LRRK2-mediated neurodegeneration and dysfunction of dopaminergic neurons in a Caenorhabditis elegans model of Parkinson's disease
    2010
    RESTRICTED
    Title: LRRK2-mediated neurodegeneration and dysfunction of dopaminergic neurons in a Caenorhabditis elegans model of Parkinson's disease
    Author(s): Chen Yao, Rabih El Khoury, Wang Wen, Tara A. Byrd, Elizabeth A. Pehek, Colin Thacker, Xiongwei Zhu, Mark A. Smith, Amy L. Wilson-Delfosse, Shu G. Chen
    Journal Name: Neurobiology of Disease
    Publisher: Elsevier BV
    Vol: 40
    Issue #: 1
    Start Page: 73
    End Page: 81
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.nbd.2010.04.002
    Best OA location URL: https://europepmc.org/articles/pmc2926296?pdf=render
    Citation Count: 125
  • Toxicological and pathophysiological roles of reactive oxygen and nitrogen species
    2010
    RESTRICTED
    Title: Toxicological and pathophysiological roles of reactive oxygen and nitrogen species
    Author(s): Ruth Roberts, Robert A. Smith, Stephen Safe, Csaba Szabó, Ronald B. Tjalkens, Fredika M. Robertson
    Journal Name: Toxicology
    Publisher: Elsevier BV
    Vol: 276
    Issue #: 2
    Start Page: 85
    End Page: 94
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1016/j.tox.2010.07.009
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8237863
    Citation Count: 174
  • Urate: a novel biomarker of Parkinson’s disease risk, diagnosis and prognosis
    2010
    RESTRICTED
    Title: Urate: a novel biomarker of Parkinson’s disease risk, diagnosis and prognosis
    Author(s): Sara Cipriani, Xiqun Chen, Michael A. Schwarzschild
    Journal Name: Biomarkers in Medicine
    Publisher: Future Medicine Ltd
    Vol: 4
    Issue #: 5
    Start Page: 701
    End Page: 712
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.2217/bmm.10.94
    Best OA location URL: https://europepmc.org/articles/pmc3049925?pdf=render
    Citation Count: 119
  • Postural instability/gait disturbance in Parkinson's disease has distinct subtypes: an exploratory analysis
    2010
    RESTRICTED
    Title: Postural instability/gait disturbance in Parkinson's disease has distinct subtypes: an exploratory analysis
    Author(s): Stewart A. Factor, N. Kyle Steenland, Donald S. Higgins, Eric Molho, Denise M. Kay, Jennifer S. Montimurro, Anne Rosén, Cyrus P. Zabetian, Haydeh Payami
    Journal Name: Journal of Neurology, Neurosurgery & Psychiatry
    Publisher: BMJ
    Vol: 82
    Issue #: 5
    Start Page: 564
    End Page: 568
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1136/jnnp.2010.222042
    Best OA location URL: https://europepmc.org/articles/pmc4646086?pdf=render
    Citation Count: 89
  • Estimation of Particulate Mass and Manganese Exposure Levels among Welders
    2010
    RESTRICTED
    Title: Estimation of Particulate Mass and Manganese Exposure Levels among Welders
    Author(s): Angela Hobson, Noah S. Seixas, David A. Sterling, Brad A. Racette
    Journal Name: The Annals of Occupational Hygiene
    Publisher: Oxford University Press (OUP)
    Vol:
    Issue #:
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1093/annhyg/meq069
    Best OA location URL: https://academic.oup.com/annweh/article-pdf/55/1/113/11209915/meq069.pdf
    Citation Count: 36
  • Heterogeneous neuropathological findings in Parkinson’s disease with mild cognitive impairment
    2010
    RESTRICTED
    Title: Heterogeneous neuropathological findings in Parkinson’s disease with mild cognitive impairment
    Author(s): Charles H. Adler, John N. Caviness, Marwan N. Sabbagh, Holly A. Shill, Donald J. Connor, Lucia I. Sue, Virgilio Gerald H. Evidente, Erika Driver‐Dunckley, Thomas G. Beach
    Journal Name: Acta Neuropathologica
    Publisher: Springer Science and Business Media LLC
    Vol: 120
    Issue #: 6
    Start Page: 827
    End Page: 828
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1007/s00401-010-0744-4
    Best OA location URL: https://europepmc.org/articles/pmc3100801?pdf=render
    Citation Count: 77
  • Calcium channel blocker use and risk of Parkinson's disease
    2010
    RESTRICTED
    Title: Calcium channel blocker use and risk of Parkinson's disease
    Author(s): Kelly Claire Simon, Xiang Gao, Honglei Chen, Michael A. Schwarzschild, Alberto Ascherio
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 25
    Issue #: 12
    Start Page: 1818
    End Page: 1822
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1002/mds.23191
    Best OA location URL: https://europepmc.org/articles/pmc2939261?pdf=render
    Citation Count: 39
  • Early‐onset L‐dopa‐responsive parkinsonism with pyramidal signs due to ATP13A2, PLA2G6, FBXO7 and spatacsin mutations
    2010
    RESTRICTED
    Title: Early‐onset L‐dopa‐responsive parkinsonism with pyramidal signs due to ATP13A2, PLA2G6, FBXO7 and spatacsin mutations
    Author(s): Coro Paisán-Ruı́z, Rocio Guevara, Monica Federoff, Haşmet Hanağası, Farzad Sina, Elahe Elahi, Susanne A. Schneider, Petra Schwingenschuh, Nin Bajaj, Murat Emre, Andrew Singleton, John Hardy, Kailash P. Bhatia, Sebastian Brandner, Andrew J. Lees, Henry Houlden
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 25
    Issue #: 12
    Start Page: 1791
    End Page: 1800
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1002/mds.23221
    Best OA location URL: https://europepmc.org/articles/pmc6005705?pdf=render
    Citation Count: 224
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