To save researchers time and resources, The Michael J. Fox Foundation has made a number of tools available to the scientific community at low cost, with rapid delivery.
Helpful Resources
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Sponsored Tools Program
Learn more about how MJFF can help share your tools.
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Tools Consortium
MJFF is working with industry to develop priority tools.
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Preclinical Models
Learn more about the various in vivo models used in Parkinson's disease research.
Find a Research Tool
Filter by Tool Type or Gene/Protein Type to Organize Results
* = MJFF does not control pricing or terms of availability for this tool.
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LRRK2 pS955 Phosphospecific Antibody
Rabbit monoclonal phosphospecific antibody directed against Serine 955 of LRRK2.
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LRRK2 KO Rat*
Homozygous rat knockout of LRRK2 created by 10 base pair deletion in Exon 30 in the Long Evans Hooded rat stain.
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LRRK2 pS935 Phosphospecific Antibody (UDD2)
Rabbit monoclonal phosphospecific antibody directed against Serine935 of LRRK2.
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LRRK2 D1994A/R1441G Mouse
Transgenic mice overexpressing both a mutant form D1994A and R1441G of human LRRK2 directed by its endogenous promoter/enhancer regions on the BAC transgene.
Please note: Although founders were positively identified through genotyping and exhibited robust mRNA expression, these projects were halted due to a lack of any appreciable protein expression.
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LRRK2 D1994A/G2019S Mouse
Transgenic mice overexpressing both a mutant form D1994A and G2019S of human LRRK2 directed by its endogenous promoter/enhancer regions on the BAC transgene.
Please note: Although founders were positively identified through genotyping and exhibited robust mRNA expression, these projects were halted due to a lack of any appreciable protein expression.
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LRRK2 pS910 Phosphospecific Antibody (1D8)
Mouse monoclonal phosphospecific antibody directed against Serine910 of LRRK2.
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LRRK2 G2019S KI Mouse
Mice expressing the human G2019S point mutation introduced into exon 41 of the mouse LRRK2 gene.
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LRRK2 pS910 Phosphospecific Antibody (UDD1)
Rabbit monoclonal phosphospecific antibody directed against Serine910 of LRRK2.
Have questions or need additional information?
Email tools@michaeljfox.org with questions and to suggest new tools for us to develop. Or visit our FAQ page.
"We have shown, thanks in part to MJFF, that researchers now have in their pantry the right ‘ingredients’, to... help to drive forward PD drug development.”
Heather Melrose, PhD
Mayo Clinic